大学共同利用機関法人 自然科学研究機構



NIBBコンファレンス - 開催リスト

The 47th NIBB Conference "Protein Phosphatases in Cellular Signaling Systems"

Organizers Masaharu Noda
Venue Okazaki Conference Center, Okazaki, Japan
Date Mar. 13-15, 2002
Tuesday March 12 2002
18:00-19:00 Registration (at the Okazaki New Grand Hotel)
19:00-21:00 Welcome Party (Only for Invited Speakers from Abroad, Organizing Committee and Director- General of National Institute for Basic Biology)
Wednesday March 13 2002
9:00-9:05 Opening Remarks
  Motoya Katsuki (Director-General of National Institute for Basic Biology, Japan)
9:05-10:05 Opening Lecture
  Nicholas K. Tonks (Cold Spring Harbor Laboratory, USA)
  "From structure to function of protein tyrosine phosphatases."
10:05-10:20 Coffee Break
10:20-12:00 Session A: Disease and phosphatases, part I
1.  10:20-11:00 Benjamin G. Neel (Beth Israel Deaconess Medical Center, USA)
  "Biological functions of non-receptor PTPs."
2.  11:00-11:30 Hideki Matsui (Okayama Univ., Japan)
  "The protein therapy inhibited myocardiac hypertrophy and protected pancreatic islet transplants through calcineurin and NF-AT cascade."
3.  11:30-12:00 Masaharu Noda (National Institute for Basic Biology, Japan)
  "Substrate screening and functional analysis for PTPζ(RPTPβ)."
12:00-13:40 Lunch
13:40-15:00 Session A: Disease and phosphatases, part II
4.  13:40-14:20 Stephane Schurmans (IRIBHN,IBMM, Belgium)
  "SHIP2 and insulin sensitivity: a role in type II diabetes mellitus?"
5.  14:20-15:00 Anna A. DePaoli-Roach (Indiana Univ., USA)
  "Role of protein phosphatase-1 in control of glycogen metabolism and cardiac function: Insights from transgenic and knockout mouse models."
15:00-15:20 Coffee Break
15:20-16:40 Session B: Protein phosphatases and neural function
6.  15:20-16:00 John L. Bixby (Univ. of Miami, USA)
  "Receptor tyrosine phosphatases in vertebrate axon growth."
7.  16:00-16:40 Shirish Shenolikar (Duke Univ., USA)
  "Elaborating the functions of protein phosphatase-1 in hippocampal plasticity."
17:40-17:00 Coffee Break
17:00-18:10 Session C: Cancer and phosphatases
8.  17:00-17:40 Ramon Parsons (Columnia Univ., USA)
  "PTEN and neoplasia."
17:40-18:10 Tomohiko Maehama (Tokyo Metropolitan Institute of Medical Science, Japan)
  "A novel tumor suppressor candidate interacting with the lipid phosphatase PTEN."
18:30-20:30 Banquet
Thursday March 14, 2002
9:00-10:00 Special Lecture
  Joseph Schlessinger (Sterling Hall of Medicine, USA)
  "Cellualar signaling by tyrosine phosphorylation."
10:00-10:20 Coffee Break
10:20-12:00 Session D: Regulation of MAPK pathways by phosphatases
7.    10:20-10:50 Hiroshi Shima (Hokkaido Univ., Japan)
  "Characterization of MKP-7, which shuttles between the nucleus and the cytoplasm."
8.    10:50-11:20 Masato Ogata (Osaka Univ., Japan)
  "Essential roles of MAP kinase-specific tyrosine phosphatases in mice."
6.    11:20-12:00 Alex Hajnal (Univ. of Züich, Switzerland)
  "The function of the C.elegans MAP kinase phosphatase LIP-1 during germline and vulval development."
12:00-13:30 Lunch
13:30-14:50 Session E: Chemical approach to the protein phosphorylation
7.    13:30-14:10 Terrence R. Burke, Jr. (National Cancer Institure, USA)
  "Phosphotyrosyl mimetics in the design of protein-tyrosine phosphatase inhibitors."
8.    14:10-14:50 Christin A. Frederick (Dana-Farber Cancer Institute, USA)
  "Structure of the cytoplasmic region of CD45."
14:50-15:05 Cofee Break
15:05-17:15 Session F: Regulation of vascular and immune systems by phosphatases
9.    15:05-15:45 Thomas O. Daniel (Immunex Corporation, USA)
  "Receptor tyrosine phosphatase, CD148: a critical regulator of vascular development and neovascularization."
10.  15:45-16:15 Toshio Watanabe (Tohoku Univ., Japan)
  "Abnormal angiogenesis but intact hematopoietic potential in PTPb2/CD148 deficient mice."
11.  16:15-15:45 Seiji Inui (Kumamoto Univ., Japan)
  "Function of phosphatase 2Ac-associated alpha4 in humoral immune response."
12.  15:45-17:15 Hidetaka Yakura (Tokyo Metropolitan Institute for Neuroscience, Japan)
  "Novel, dynamic regulation of Src-family tyrosine kinases by CD45."
17:15-18:15 Poster session
19:00 Dinner (For Invited Speakers and Organizing Committee, at Tsukushi)
Friday March 15 2002
9:00-11:55 Session G: Regulation of signaling pathways by phosphatases
13.  9:00-9:30 Tatsuya Maeda (Tokyo Univ., Japan)
  "Genetic analysis of the TOR pathway using Tap42p/a4, a non-conventional regulatory subunit of PP2A."
14.  9:30-10:00 Reiko Sugiura (Kobe Univ., Japan)
  "Functional analysis of calcineurin-mediated signaling pathway using fission yeast as a model system."
15.  10:00-10:30 Shinri Tamura (Tohoku Univ., Japan)
  "Molecular cloning of a novel member of protein phosphatase 2C family enriched in testicular germ cells."
10:30-10:45 Coffee Break
16.  10:45-11:15 Takashi Matozaki (Gunma Univ., Japan)
  "The physiological role of SHPS-1."
17.  11:15-11:55 Rob Hooft van Huijsduijnen (Serono Pharmaceutical Research Institute, Switzerland) 
  "Identification of protein tyrosine phosphatases with specificity for the ligand- activated growth hormone receptor."
11:55-12:10 Concluding remarks
  Haruo Saito (Institute of Medical Science, University of Tokyo)
12:15-13:45 Lunch