基礎生物学研究所
| Organizers | Taisen Iguchi |
|---|---|
| Venue | Okazaki Conference Center, Okazaki, Japan |
| Date | Mar. 3-5, 2001 |
| Program | |
| Saturday March 3, 2001 | |
| 10:00- | Registration |
| Session1 (Opened to the Public) | |
| Chairperson: Taisen lguchi | |
| 13:00-13:10 | Opening Address: Hideo Mohri (Natl. Inst. for Basic Biol.) |
| 13:10-13:50 | Taisen Iguchi (Center for Integrative Bioscience, ONRI) |
| "Environmental Endocrine Disruptors Issues in Japan" | |
| 13:50-14:30 | Yoko Kawamura (Natl. Inst. of Health Science) |
| "Possible Endocrine Disruptors from Food Containers" | |
| 14:30-14:20 | Break |
| 14:20-15:20 | Louis J. Guillette Jr. (Univ. of Florida, USA) |
| "Contaminants and Wildlife" | |
| 15:20-16:00 | Saburo Matsui (Kyoto Univ.) |
| "Environmental Risk Management" | |
| Poster Session (16:30-18:30) | |
| 16:30-16:40 | Greeting: Hirozo Ueda (Ministry of the Environment) |
| 16:40-17:10 | Tyrone Hayes (Univ. of Calif. at Berkeley, USA) |
| "Atrazine Inhibits Development of the Male Larynx in Xenopus Laevis: Possible Disruption of Steroidogenesis" | |
| 17:10-18:30 | Meeting (Ministry of the Environment) |
| 18:30-20:00 | Casual Dinner |
| 20:00- | Meeting |
| Sunday March 4, 2001 | |
| 9:00- | Registration |
| Chairperson: Taisen lguchi | |
| 09:30-09:45 | Opening Address: Hideo Mohri (Natl. Inst. for Basic Biol.) |
| 09:45-10:00 | Howard A. Bern (Univ. of Calif. at Berkeley, USA) |
| "Some Problems in Research on Endocrine Disruptors" | |
| Session2-a | |
| Chairpersons: Bruce Blumberg, Ken-Ichirou Morohashi | |
| 10:00-10:30 | John McLachlan (Tulane and Xavier Univ., USA) |
| "Hormones and Developmental Programming: a Key to Understanding Endocrine Disruption" | |
| 10:30-11:00 | John Couse (Natl. Inst. of Envion. Health, USA) |
| "The role of Estrogen receptor-_ in the Effects of Neonatal Diethylstilbestrol Exposure in the Female Reproductive Tract: Insights from Studies of the ER_-knockout mice" | |
| 11:00-11:30 | Bruce Blumberg (Univ. of California, Irvine, USA) |
| "Metabolism of EDC Mediated by the Steroid and Xenobiotic Receptor, SXR" | |
| 11:30-11:50 | Hisashi Masuyama (Okayama Univ.) |
| "Potential Roles of Pregnane X Receptor in Pregnancy and Endocrine Disrupting Mechanism" | |
| 11:50-12:10 | Jennifer Fox (Tulane and Xavier Univ., USA) |
| "Phytochemical Signaling and Symbiotic Gene Activation Are Interrupted by Endocrine Disrupting Chemicals" | |
| 12:10-12:30 | Ken-Ichirou Morohashi (Natl. Inst. for Basic Biol.) |
| "Transcription Factors Implicated in Gonad Differentiation" | |
| 12:30-13:30 | Lunch |
| Session2-b | |
| Chairpersons: Yoshitaka Nagahama, Hajime Watanabe | |
| 13:30-13:50 | Hajime Watanabe (Center for Integrative Bioscience, ONRI) |
| "Effects of Selected Endocrine Disrupting Chemicals on Gene Expression in Mouse Reproductive Tracts" | |
| 13:50-14:10 | Gen Yamada (Kumamoto Univ.) |
| "How to Control External Genitalia Morphogenesis: Control "Atrazine Inhibits Development of the Male | |
| 14:10-14:30 | Masaru Wada (Tokyo Medical and Dental Univ.) |
| "Seeking a Reliable Method to Detect Endocrine Disruption in Avian Species Assessment of Female specific Yolk Proteins in Male Japanese Quail" | |
| 14:30-14:50 | Hideko Sone (Natl. Inst. for Environmental Studies) |
| "Effects of In utero and Lactational Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Sexual Differentiation of The Male Rat Brain" | |
| 14:50-15:10 | Toshitaka Ikeuchi, Yoshitaka Nagahama (Natl. Inst. for Basic Biol.) |
| "Two Androgen Receptor Subtypes in Teleost Fish: Characterization, Interaction and Potential Role in Sex Differentiation" | |
| 15:10-15:40 | Graham Young (Univ. of Otago, New Zealand) |
| "Steroidogenic Acute Regulatory Protein (StAR) and Steroidogenic Enzymes of Fish: StARting to Understand their Regulation by Sex Steroids" | |
| 15:40-16:10 | Coffee Break |
| Chairpersons: Daniel B. Pickford, Toshihiro Horiguchi | |
| 16:10-16:30 | Masaru Nakamura (Univ. of the Ryukyus) |
| "Gonadal Sex Differentiation in Fish and the Effects of Environment Endocrine Disrupters" | |
| 16:30-16:50 | Toshihiro Horiguchi (Natl. Inst. for Environmental Studies) |
| "Endocrine Disruption and Populations Decline in Gastropod Molluscs, Caused by Organotins from Antifouling Paints" | |
| 16:50-17:20 | Caren Helbing (Univ. of Victoria, Canada) |
| "Molecular Approaches to the Detection of Endocrine Disrupting Effects in Frogs" | |
| 17:20-17:50 | Daniel B. Pickford (AstraZeneca Freshwater Quarry, UK) |
| "Effects of 17 α -Ethinylestradiol on Larval Growth, Development and Sexual Differentiation in Xenopus laevis" | |
| 18:00-20:00 | Banquet |
| Monday March 5, 2001 | |
| Session3-a | |
| Chairpersons: Louis J. Guillette Jr., Chisato Mori | |
| 09:00-09:30 | Louis J. Guillette Jr. (Univ. of Florida, USA) |
| "Contaminantsand Wildlife: Lessons from Embryos" | |
| 09:30-10:00 | Susan Jobling (Brunel Univ., UK) |
| "The Consequences of Sexual Disruption in Wild Fish" | |
| 10:00-10:30 | Charles Tyler (Univ. of Exeter, UK) |
| "The Causes and Mechanisms of Sexual Disruption in Fish" | |
| 10:30-11:00 | Mary Ann Ottinger (Univ. of Maryland, USA) |
| "Establishing Reliable End Points in Assessing the Effects of Endocrine Disrupting Chemicals in the Japanese Quail" | |
| 11:00-11:30 | Frederick vom Saal (Univ. of Missouri, Columbia, USA) |
| "Effects of Diet and Endocrine Disruptors on Development of the Reproductive System in Mice" | |
| 11:30-11:50 | Chisato Mori (Chiba Univ.) |
| "Increasing Importance of Biological Markers and DNA Microarray Analysis for Assessing Fetal Exposure on Endocrine Disruptors" | |
| 11:50-12:10 | Osamu Tsutsumi (Univ. of Tokyo) |
| "Effects of Endocrine Disruptors on Preimplantaion Embryo Development" | |
| 12:10-12:40 | Shanna H. Swan (Univ. of Missouri, Columbia, USA) |
| "Temporal Trends and Geographic Variation in Semen Quality: Recent Findings" | |
| 12:40-13:40 | Lunch |
| Session3-b | |
| Chairpersons: Ann Cheek, Taisen Iguchi | |
| 13:40-14:00 | Shinsuke Tanabe (Ehime Univ.) |
| "Contamination and Toxic Effects of Endocrine Disrupters in Wildlife" | |
| 14:00-14:30 | Ann Cheek (Southeastern Louisiana Univ., USA) |
| "Experimental Evalution of Vitellogenin as a Predictive Biomaker for Reproductive Disruption" | |
| 14:30-15:00 | Yhun Y. Sheen (Ewha Womans Univ., Korea) |
| "pERE-Luc Stably Transfected MCF-7 Cells and pCYPlAl-Luc Transfected Hepa I Cells for the Assessments of Estrogen and Dioxin Like Activities of Environmental Chemicals and Korean River Water" | |
| 15:00-15:30 | Coffee Break |
| Chairpersons: Kouji Arizono, Hiroaki Aoyama | |
| 15:30-16:00 | Kyung-Sun Kang (Seoul Natl. Univ., Korea) |
| "Developmental Impairments of Reproductive Tracts on the Fl Offspring Rats Perinatally Exposed to Endocrine Disrupters" | |
| 16:00-16:20 | Kouji Arizono (Pref. Univ. of Kumamoto) |
| "The Estrogen Activity on Feeding Diet Evaluated with Vitellogenin Assay in vivo and Yeast two-Hybrid Assay in vitro" | |
| 16:20-16:40 | Hiroaki Aoyama (The Inst. of Environmental Toxicology) |
| "An approach for predicting endocrine disrupting activities of pesticides" | |
| 16:40-17:00 | Jun Kanno (Natl. Inst. of Health Science) |
| "Endocrine Disruption as a Receptor-Mediated Toxicity" | |
| 17:00-17:20 | Closing Remarks: John McLachlan (Tulane and Xavier Univ., USA) |
