40BBL00102
Developmental and Regenerative Biology
2nd Half
1 Credit
47 Basic Biology Program
Fujimori Toshihiko, Takahashi Hiroki

 

■Outline
A single fertilized egg undergoes division, differentiation, and morphogenesis under precise regulatory control to develop into a multicellular adult, which in turn ensures the continuity of the next generation through reproduction. This lecture explores the regulatory mechanisms governing axis formation, cell differentiation, programmed cell death, and morphogenesis in both animals and plants. Furthermore, we will examine the metabolic pathways that drive developmental processes, alongside the principles of universality and diversity shaped by evolution. The course also addresses reproductive strategies across various taxa, as well as the mechanisms of regeneration and stem cell potency in comparison to embryonic development. This course will be conducted entirely online.

 

■Learning objectives
Elucidate the processes of ontogeny in both animals and plants.
Explain the mechanisms of regeneration observed across various multicellular organisms.
Analyze the similarities and differences between embryonic development and regeneration through specific case studies.

 

■Grading policy
The achievement of the objectives will be evaluated based on questions and answers during the lectures and reports submitted at the end of each lecture.

 

■Lecture Plan
Lectures are generally held on Thursdays from 10:00 to 12:00. Detailed schedules will be announced at a later date.

Masayuki Miura: "Mechanisms and Roles of Programmed Cell Death"
Masaki Ishikawa: "Regulatory Mechanisms Supporting Plant Cell Plasticity"
Takehiko Kanazawa: "Molecular Basis for the Evolution and Diversification of Plant Development"
Shinnosuke Suzuki: "The Role of Stem Cells in Development"
Toshihiko Fujimori: "Early Mammalian Development"
Ken-ichi Suzuki: "Similarities and Differences Between Organogenesis and Organ Regeneration: Using Amphibian Limbs as a Model"
Rieko Ajima: "Regulation of Mouse Development by Wnt Signaling"
Noriyuki Kinoshita: "Uterine Epithelial Dynamics During the Process of Mouse Embryo Implantation"
Hiroki Takahashi: "The Role of the Notochord in Chordates"
Shigenori Nonaka: "Mechanisms of Left-Right Asymmetry Determination in Development"
Hiromasa Shikata: "Plant Development and Growth Based on Cell Polarity"
Yasuhiro Kamei: "Imaging and Optogenetic Microscopy Techniques in Developmental Biology Research"

 

■Location
Online

 

■Language
English

 

■Textbooks and references
Not specified

 

■Notes for students of other programs
Students from other courses are welcome to attend. Although it is not difficult to understand the basics of the lecture as it contains basic content, self-study after the course is recommended, especially for students majoring in other fields.
Students other than Basic Biology Program who wish to enroll in this class should contact Graduate Student Affairs Section, Okazaki Administration Center (r7139@orion.ac.jp) during the registration period.

 

■Contact for Course Inquiries
Toshihiko Fujimori (fujimori@nibb.ac.jp)