Developmental and Regenerative Biology
2nd Half
1 Credit
47 Basic Biology Program
Fujimori Toshihiko, Yoshida Shosei, Kinoshita Noriyuki,
Suzuki Kenichi, Ebine Kazuo, Takahashi Hiroki
Four-grade evaluation
Level : Level 3
Competence : Academic expertise
■Outline
A single cell, the fertilized egg, divides, differentiates, and develops through morphogenesis, under complex and precise regulation, into an adult multicellular organism that leads to the next generation through reproduction. In this lecture, we will discuss the regulatory mechanisms of axis formation, cell differentiation, and morphogenesis in the early stages of development of multicellular organisms such as animals and plants, metabolic regulatory mechanisms that drive and maintain development, and the universality and diversity of organisms that have emerged through evolution. The course will also cover various issues related to reproduction in a wide variety of organisms, including animals and plants. The mechanisms behind the phenomenon of reproduction observed in many multicellular organisms will be discussed in comparison with developmental phenomena. This course will be offered as an online lecture.
■Learning objectives
Explain ontogeny in animals and plants. Explain the phenomena of regeneration observed in multicellular organisms. Understand the similarities and differences between development and regeneration using examples.
■Grading policy
The achievement of the objectives will be evaluated based on questions and answers during the lectures and reports submitted at the end of each lecture.
■Lecture Plan
Online lecture(Thursday, 10:00-12:00), Lecturers and titles are as follows
Oct.17
10:00- Kiyokazu Agata Unifying the principles of Developmental and Regenerative Biology
Oct.24
10:00- Tomomi Tsubouchi Cellular differentiation, reprogramming and cell cycle
11:00- Toshihiko Fujimori Plasticity in embryonic development
Oct.31
10:00- Kazuo Ebine Molecular mechanisms of plant reproduction
11:00- Hiroki Takahashi Development of the notochord
Nov.7
10:00- Kenichi Suzuki Differences between organ development and regeneration: a lesson from the amphibian limb as a model
11:00- Shinnosuke Suzuki The roles of stem cells during development
Nov.14
10:00- Shigenori Nonaka Determination of the left-right asymmetry
11:00- Rieko Ajima Regulation of mouse development by Wnt signaling
Nov.21
10:00- Noriyuki Kinoshita Molecular dynamics in the mouse uterine epithelia
11:00- Shosei Yoshida Tissue stem cells and their niche
■Location
Online
■Language
English
■Textbooks and references
■Notes for students of other programs
Students from other courses are welcome to attend. Although it is not difficult to understand the basics of the lecture as it contains basic content, self-study after the course is recommended, especially for students majoring in other fields.
Students other than Basic Biology Program who wish to enroll in this class should contact Graduate Student Affairs Section, Okazaki Administration Center (r7139@orion.ac.jp) during the registration period.
■Others
Lecturers: Kiyokazu Agata, TomomiTsubouchi,Toshihiko Fujimori, Kazuo Ebine, Hiroki Takahashi, Kenichi Suzuki, Shinnosuke Suzuki, Shigenori Nonaka, Rieko Ajima, Noriyuki Kinoshita, Shosei Yoshida
■Contact for Course Inquiries
Toshihiko Fujimori (fujimori@nibb.ac.jp)
