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National Institutes of Natural Sciences

National Institute for Basic Biology

PhD Program

Syllabus

Bioinformatics

This lecture will not be offered in 2024.
The following is the information on the lecture offered in 2023.

Bioinformatics
2nd Half
1 Credit
47 Basic Biology Program
S. Shigenobu, I. Uchiyama, M. Nozawa
Four-grade evaluation
Level : Level 2
Competence : Academic expertise
 
■Outline
Mainly focusing on sequence data analyses, both theoretical background and practical skills of basics bioinformatics are introduced through lectures and hands-on tutorials. Also, students can learn how to apply bioinformatics to genome and transcriptome analyses. This is a two-day intensive course involving both lectures and hands-on.
 
■Learning objectives
The following three objectives are attained through lectures and hands-on tutorials.
1. Understand basic principles in biological sequence analyses.
2. Master basic skills for genomic and transcriptomic analyses.
3. Learn the current state of genomics and bioinformatics research, and discuss the prospects for life science in the Big Data era.
 
■Grading policy
In addition to sufficient attendance to the lecture, students must complete an assignment to get credit for the course. Activity in the lectures and tutorials: 50%; An assignment 50%.
 
■Lecture Plan
This is the 2-day intensive course.
November 1st (Wed), 2023 -- November 2nd (Thu), 2023
Place: Seminar Room 1, Myodaiji (132-134) (@NIBB)
 
Day 1
#1: Introduction / Biological sequence analysis 1 (pairwise alignment)
#2: Biological sequence analysis 2 (multiple alignment, motifs)
#3: Biological sequence analysis 3 (molecular evolution)
#4: Genome analysis 1 (genome assembly and gene prediction)
 
Day 2
#5: Genome analysis 2 (gene annotation and ortholog analysis)
#6: Transcriptome analysis 1 (RNA-seq and other omics technologies)
#7: Transcriptome analysis 2 (clustering, multivariate analysis)
#8: Biological databases and current topics (big data and AI in biology)
 
Lecturer: Dr. Shuji Shigenobu (SOKENDAI / NIBB), Dr. Ikuo Uchiyama (SOKENDAI / NIBB), Dr. Masafumi Nozawa (Tokyo Metropolitan Univ; visiting lecturer)
 
■Location
National Institute for Basic Biology (Room: TBA)
 
■Language
English 
 
■Textbooks and references
No specific literatures are recommended.
Familiarity with basic UNIX command line operations is recommended.
 
■Notes for students of other programs
Students other than Basic Biology Program who wish to enroll in this class should contact Graduate Student Affairs Section, Okazaki Administration Center (r7139@orion.ac.jp) during the registration period.
 
■Keyword
bioinformatics
genomics
transcriptome
evolution
big data