Attend the international conference (The 69th NIBB Conferece, Nov 6-7, 2025, Venue: Okazaki Conference Center) to engage with presentations highlighting cutting-edge research findings regarding the “cellular vitality regulation research”, and to participate in discussions with eminent researchers in this field.
For details, please refer to the following website;
https://nibbconf69.nibb.ac.jp/
Students are anticipated to listen to presentations by leading researchers who aim to elucidate the mechanisms of cellular vitality regulation across a broad spectrum of scales from molecular to individual, and learn about the concepts and methods that are important for conducting research in “Trans-Scale Biology”. Moreover, students will have the opportunity to comprehend novel findings and the subsequent questions that emerge from the research outcomes. Furthermore, students will gain insights into the dynamics of research communication in the context of an international gathering.
Participants in the international conference are required to submit a report. Grades will be assigned based on the contents of the report. The report should be written on one A4 sheet and sent by email to Professor Masayuki Miura (miura@nibb.ac.jp) by December 8th.
■Lecture Plan
Cells in population or multicellular organisms possess a phenomenon in which they lose their vigor. Why is this cell vigor-loss mechanism conserved in multicellular organisms? During development, a large amount of programmed cell death occurs, playing a crucial role in processes such as morphogen switching, morphogenetic movements, and the elimination of cells that have failed to differentiate. In adults, cell competition functions as a tumor suppression mechanism by removing precancerous cells.
Additionally, maintaining stem cells involves inducing selective cell death to preserve their quality. Organisms have a maximum lifespan beyond which they cannot survive. Although aging has been evolutionarily conserved, our understanding of its biological role is still limited.
In addition to cell death and organismal death, cells and organisms have developed various responses to cope with environmental changes and stress, which can lead to a decline in vigor. In extreme cases, they reduce their overall metabolism and enter states such as dormancy or hibernation.
The aim of this conference is to discuss how the regulation of cell vigor influences phenotypes at the level of cell populations and organisms, drawing on research in areas such as cell death, control of cell fate, stem cells, cellular stress responses, aging and hibernation.
Approaches to researching cell vigor span a wide range of fields, including live imaging, genetics, molecular biology, biochemistry and metabolism. In order to deepen our understanding of the mechanisms underlying the regulation of cell vigor, theworkshop will focus on cellular vitality regulation, and will provide students with anopportunity to gain an integrated understanding from an interdisciplinary approach.Moreover, students will actively join the discussion regarding current results andproblems, as well as future research directions.
■Location
Okazaki Conference Center
■Language
English
■Textbooks and references
There are no specified textbooks or reference books for this course.
■Notes for students of other programs
Students other than Basic Biology Program who wish to enroll in this class should contact Graduate Student Affairs Section, Okazaki Administration Center (r7139@orion.ac.jp) during the registration period.
■Related URL
https://nibbconf69.nibb.ac.jp/
■Contact for Course Inquiries
Regarding the lecture contents:
Masayuki Miura
miura@nibb.ac.jp
Regarding participation in the conference:
Kiyoshi Tatematsu
ktatem@nibb.ac.jp
nibbconf@nibb.ac.jp
