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大学共同利用機関法人 自然科学研究機構

基礎生物学研究所

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EMBO | COB Workshop "Plant tropisms"

Organizers Organizers:
森田(寺尾)美代(基礎生物学研究所)
Christian Fankhauser (Université de Lausanne, CH)
Claus Schwechheimer (Technical University of Munich, DE)
Co-Organizer:
立松圭(基礎生物学研究所)
Venue 愛知県岡崎市・岡崎コンファレンスセンター
Date July 9 – 12, 2024
Link Official Website (https://meetings.embo.org/event/24-plant-tropisms)
Poster EMBO | COB Workshop
【About the Workshop】
Since Charles Darwin’s “The Power of Movement in Plants”, it has become evident that plants use elaborate mechanisms to control their growth in response to environmental cues such as light (phototropism), gravity (gravitropism), or touch (thigmotropism). Essential for tropic growth is the differential distribution of the phytohormone auxin, which regulates differential cell elongation within tissues. With advances in the molecular understanding of tropic growth, this has become an attractive field for biophysicists.
 
Still much remains to be understood about how stimulus perception leads to tropic growth. In the past years, there have been many new relevant findings, which now need to be brought together to foster interactions between experimenters and disciplines: E.g. new molecular players have been identified (LAZY proteins, AGC1 kinases); new mechanisms of the respective signaling pathways have become apparent (phototropin kinase targets, phosphorylation control of cellular events); previously unknown rapid auxin responses have been observed; structural analyses of auxin transporters have uncovered the mechanisms underlying auxin transport regulation; physicists have successfully modelled tropic growth combining theory and biology.
 
In our EMBO workshop “Plant Tropisms”, we will bring together biologists and modelers to report on their progress and discuss new findings on tropism regulation.


【開催報告】
ダーウィンの「The Power of Movement in Plants」以来、植物の環境応答である屈性は植物生理学における重要課題の一つです。モデル植物を中心とした研究から分子的理解が進んだことで、この分野は理論生物学者、生物物理学者にとっても魅力的な分野となりました。本EMBO | Company of Biologists Workshopでは、実験者間また学問分野間の相互作用を促進するために、世界中から屈性研究者が集い、植物屈性に関する新たな知見について議論することを目的としました。
 
本ワークショップは4日間岡崎コンファレンスセンターで開催され、世界中のさまざまな地域から120名が参加しました(ヨーロッパ:35名、米国:2名、アジア:73名(日本:55名))。このワークショップはハイブリッドイベントとして実施され、会場参加者は82名、オンライン参加者は38名でした。18名の招待講演者(日本:5名)とポスター発表から選ばれた19名(日本:8名)が口頭発表を、また58名(日本:29名)がポスター発表を行いました。41名の大学院生、27名のポスドクおよび助教を含む68名の若手研究者が参加し、キャリアステージの異なる研究者間の活発な国際研究交流が行われました。中国、イスラエル、チェコから参加した3人の新進気鋭の若手研究者が司会を務めたグループディスカッションを含め、いずれのセッションにおいても活発な議論が繰り広げられました。その中で、実験室と自然環境(例えば土壌環境)のギャップを考慮すべきであるという重要な指摘がなされました。また、屈性における複数の内在性および外在性シグナルの統合による成長反応の複雑性が強調され、生物学的データと成長モデリングの統合が、次の大きな飛躍に重要な意味を持つという認識が共有されました。
 
終了後のアンケートでは、参加者の67%が「excellent」と評価し、さらに31%が「very good」と評価しました。さらに具体的コメントからもこのワークショップの科学的質の高さが評価されました。多くの参加者が、この最初の『Plant Tropisms』ワークショップは大成功であると評し、この勢いに乗って2-3年の内に次回会議を開催することを希望し、開催地と現地の主催者候補の議論が既になされました。このように、本ワークショップが屈性研究コミュニティーを先導・活性化したことは明らかです。
 
オーガナイザー 森田(寺尾)美代(基礎生物学研究所 植物環境応答研究部門)
 

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Program
Day 1 | 9 July 2024
13:00 Registration
   
13:45-14:00 Opening Remarks
  Miyo T. Morita and Kiyokazu Agata (National Institute for Basic Biology, JP)
   
Session 1  
Chair: Stacey Harmer (University of California, Davis,US)
14:00-14:30 Phototropism: from light gradient formation in a photosensitive tissue to regulated asymmetric growth
  Christian Fankhauser (Université de Lausanne, CH)
   
14:30-15:00 Type 2C protein phosphatases regulate directional light sensing in Arabidopsis
  John M. Christie (University of Glasgow, UK)
   
15:00-15:30 Functional analysis of intrinsically disordered regions of NONPHOTOTROPIC HYPOCOTYL3 protein
  Tatsuya Sakai (Niigata University, JP)
   
15:30-15:45 Characterization of blue light-induced paraheliotropic leaf movements in soy bean
  Shin-ichiro Inoue (Saitama University, JP)
   
15:45-16:15 Coffee break
   
Session 2  
Chair: Wei Xuan (Nanjing Agricultural University, CN)
16:15-16:45 How plants respond to salt
  Christa Testerink (Wageningen University and Research, NL); Online talk
   
16:45-17:15 Deciding where to (g)row; Modeling the tug of war between halotropism and gravitropism
  Kirsten ten Tusscher (Utrecht University, NL); Online talk
   
17:30-19:00 Mixer with snacks
   
19:00 Transfer to City and hotels (free time for dinner)
   
Day 2 | 10 July 2024
9:00 Registration
   
Session 3  
Chair: Hidehiro Fukaki (Kobe University, JP)
9:00-9:30 The dynamics of auxin signaling and response during root gravitropism
  Matyáš Fendrych (Charles University, CZ)
   
9:30-9:45 Exploring the mechanisms of root bending response to gravity through quantitative analysis of cellular dynamics
  Tatsuaki Goh (Nara Institute of Science and Technology, JP)
   
9:45-10:15 Molecular mechanism of MIZU-KUSSEI1-mediated root hydrotropism in Arabidopsis
  Yutaka Miyazawa (Yamagata University, JP)
   
10:15-10:30 Auxin biosynthesis, transport and response directly attenuate hydrotropic bending of roots in the latter stages in Arabidopsis thaliana
  Kotaro Akita (Yamagata University, JP)
   
10:30-11:00 Coffee break
   
Session 4  
Chair: Keiji Nakajima (Nara Institute of Science and Technology, JP)
11:00-11:30 Lessons from underground: How do roots sense water availability?
  Malcolm J. Bennett (University of Nottingham, UK)
   
11:30-12:00 Auxin-triggered rapid cellular responses for gravitropic root bending
  Jiří Friml (Institute of Science and Technology Austria, AT)
   
12:00-13:30 Group Photo, Lunch with Meet the Speakers
   
Poster session (Odd numbers)
Chair: Kiyoshi Tatematsu (National Institute for Basic Biology, JP)
13:30-14:00 Poster Flash Talks
   
14:00-15:00 Poster Session
   
15:00-16:00 Coffee break (Poster session continued)
   
Session 5  
Chair: Hiromasa Shikata (National Institute for Basic Biology, JP)
16:00-16:30 AGC kinases and the power of movement in plants
  Claus Schwechheimer (Technical University of Munich, DE)
   
16:30-16:45 Systems approaches reveal that ABCB and PIN proteins mediate co-dependent auxin efflux
  Leah R. Band (University of Nottingham, UK); Online talk
   
16:45-17:00 AI-assisted decoding of condensate assembly in the plant phototropic response
  Prabha Manishankar (The Center for Plant Molecular Biology (ZMBP), GE); Online talk
   
17:00-17:30 Transport properties of canonical PIN-FORMED proteins and the role of the loop domain in auxin transport and tropisms
  Ulrich Z. Hammes (Technical University of Munich, GE); Online talk
   
17:30-17:45 Emergence of polar auxin transport regulatory machinery before divergence of land plants
  Satoshi Naramoto (Hokkaido University, JP)
   
17:45-18:00 Engineering FRET biosensors for direct visualisation of endogenous auxin dynamics
  Max Josse (University of Cambridge, UK)
   
18:00 Transfer to City and hotels (free time for dinner)
   
Day 3 | 11 July 2024
9:00 Registration
   
Session 6  
Chair: Stefan Kepinski (University of Leeds, UK)
9:00-9:30 The physics of gravity sensing by plants: the position sensor hypothesis
  Yoël Forterre (CNRS, Aix-Marseille Université, FR)
   
9:30-10:00 Gravity sensing and signaling mediated by dynamic polarity shift of LZY
  Miyo T. Morita (National Institute for Basic Biology, JP)
   
10:00-10:15 Exploring the evolutionary process of plant gravitropism by utilizing the basal land plant, Physcomitrium patens
  Kanta Suemitsu (Hokkaido University, JP)
   
10:15-10:45 Coffee break
   
Session 7  
Chair: Satoshi Naramoto (Hokkaido University, JP)
10:45-11:15 Molecular mechanisms underlying gravity sensing in plants
  Haodong Chen (Tsinghua University, CN)
   
11:15-11:30 The integration of PIN protein phosphoregulation and LAZY signalling in lateral root gravitropic setpoint angle control
  Stefan Kepinski (University of Leeds, UK)
   
11:30-12:00 Is that tree weeping or just lazy? A story about pendulous and wandering plum and peach trees.
  Courtney A. Hollender (Michigan State University, US)
   
12:00-12:15 The molecular mechanism underlying rice root tolerance to ammonium toxicity
  Wei Xuan (Nanjing Agricultural University, CN)
   
12:15-12:30 The role of polar auxin transport in cell polarity establishment in lateral root primordium formation
  Sanae Kaneta (Osaka University, JP)
   
12:30-13:45 Lunch with Meet the Speakers
   
Poster session (Even numbers)
Chair: Kiyoshi Tatematsu (National Institute for Basic Biology, JP)
13:45-14:15 Poster Flash Talks
   
14:15-15:15 Poster Session
   
15:15-16:15 Coffee break (Poster session continued)
   
Session 8  
Chair: Yutaka Miyazawa (Yamagata University, JP)
16:15-16:45 Actin-dependent organ straightening in establishing plant posture and its mechanical significance
  Haruko Ueda (Konan University, JP)
   
16:45-17:00 NEK6 provides tissue-specific growth anisotropy through its actin-dependent polar localization in Arabidopsis thaliana
  Hiroyasu Motose (Okayama University, JP)
   
17:00-17:15 KIPK AGC1 kinases suppress overbending during negative hypocotyl gravitropism
  Yao Xiao (Guangzhou University, CN); Online talk
   
17:15-17:30 Actin filaments reorganization in response to auto straightening
  Kinza Khan (University of Clermont Auvergne, FR); Online talk
   
Group Discussion  
Chair: Yasmine Meroz (Tel Aviv University, IL), Matyáš Fendrych (Charles University, CZ), and Haodong Chen (Tsinghua University, CN)
17:30-18:30 Standard in tropism research, big challenges, future of the field, interest in follow up conference, publications
   
19:00-21:00 Dinner with 1-to-1 discussion (Okazaki New Grand Hotel)
   
Day 4 | 12 July 2024
9:00 Registration
   
Session 9  
Chair: Yoël Forterre (CNRS, Aix-Marseille Université, FR)
9:00-9:30 Plant tropisms as a window on plant computational processes
  Yasmine Meroz (Tel Aviv University, IL)
   
9:30-9:45 Twining plants capitalize on circumnutations to assess mechanical properties of candidate support, and initiate a thigmotropic twining response
  Amir Ohad (Tel Aviv University, IL)
   
9:45-10:00 Molecular mechanism of apical hook development
  Pawan K. Jewaria (National Institute of Plant Genome Research Aruna Asaf Ali Marg, IN)
   
10:00-10:30 Recent research progress on the novel root tropism to explore nutrients
  Kiyoshi Yamazaki (The University of Tokyo, JP)
   
10:30-11:00 Coffee break
   
Session 10  
Chair: Christian Fankhauser (Université de Lausanne, CH)
11:00-11:30 Sunflower heliotropism as a model for understanding plant responses to natural environmental cues
  Stacey Harmer (University of California, Davis,US)
   
11:30-11:45 The clock genes, PRRs, regulate phototropin-mediated blue-light responses in Arabidopsis
  Gian Carlo F. Maliwat (Nara Institute of Science and Technology, JP)
   
11:45-12:00 Circadian clock regulates root hair elongation in Arabidopsis
  Akane Kubota (Nara Institute of Science and Technology, JP)
   
12:00-12:10 Closing Remarks
  Christian Fankhauser (Université de Lausanne, CH) and Claus Schwechheimer (Technical University of Munich, DE)
   
12:10-14:00 Lunch with Meet the Speakers
   
14:00 Departure
   
  Optional: NIBB Facility Tour (Okazaki Large Spectrograph)

The list of poster presentations can be found here.