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National Institute for Basic Biology

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The 57th NIBB Conference "The Dynamic Genome"

Organizers Takashi Horiuchi (NIBB)
Venue Okazaki Conference Center, Okazaki, Japan
Date Oct. 14-16, 2010
Link Official Website (http://www.nibb.ac.jp/conf57/index.html)
Poster The 57th NIBB Conference

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There are two forms of environmental change that affect living organisms. One is environmental change which organisms regularly experience, such as fluctuations in temperature, availability of food sources, etc. and the other are those they have not experienced before. In the former case, organisms rely on their program or genetic network which has been constructed during evolution to adapt to the changes and survive. On the other hand, when they are exposed to environmental changes they have never developed responses for (for example new pesticides), they may be virtually eradicated or only a very small percentage of them survive by developing tolerance to the severe environment. The mechanisms induced in this case are dynamic genome changes, such as recombination and mutation which probably play a central role in biological evolution. Thus, with this in mind, we titled this conference “The Dynamic Genome”, and we provided an opportunity for a discussion with more than forties international researchers active in this field. These discussions covered more complex process, such as gene amplification and mechanisms involved in proteins, such as cohesin and condensin, and gene evolution. 

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Program

 

October 14 (Thu) at Okazaki Conference Center
09:00-09:30 Registration      at the Conference Center
Chair: Takashi Horiuchi
09:30-10:30 Keynote lecture
  “Genomic Stability under Oxidative Stress”
        Mutsuo Sekiguchi (Fukuoka Dental College, Japan)
 
Session 1   (Bacterial Genome and Genome Rearrangement)
Chair: Katsuki Johzuka
10:30-11:15 “The boundaries of the Ter Domain in Bacterial Nucleoid”
 
      Hironori Niki (NIG, Japan)
11:15-11:35
Coffee Break
11:35-12:20 “Molecular Regulation of Recombinase-Mediated Strand Exchange Reactions, A Central Reaction of Homologous Recombination”
        Hiroshi Iwasaki (Tokyo inst. of Tech, Japan)
12:20-14:30
Lunch & Poster at the Conference Hall
        List of Poster titles
Chair: Hiroshi Iwasaki
14:30-15:15 “Programmed Genome Rearrangements in Tetrahymena: Links to RNAi and Transposons”
  Meng-Chao Yao (IMB, Taiwan)
   
Session 2   (Gene Amplification Ⅰ)
Chair: Meng-Chao Yao
15:15-16:00 “Regulation of Ribosomal RNA Gene Copy Number and Its Role in Modulating Genome Integrity in Yeast”
        Takehiko Kobayashi (NIG, Japan)
16:00-16:20
Coffee Break
16:20-17:05 “Gene Amplification in Chromosomal and Extrachromosomal Context”
        Noriaki Shimizu (Hiroshima Univ., Japan)
   
October 15 (Fri) at Okazaki Conference Center
Session 2   (Gene Amplification Ⅱ)
Chair: Takehiko Kobayashi
09:00-09:45 “A Comprehensive Model of Gene Amplification Centering on Double Rolling-Circle Replication (DRCR)”
        Taka-aki Watanabe (NIBB, Japan)
09:45-10:30 “Double Rolling Circle Replication (DRCR) is Recombinogenic”
        Takashi Horiuchi (NIBB, Japan)
10:30-10:50
Coffee Break
   
Session 3   (Condensin and Cohesin)
Chair: Tatsuya Hirano
10:50-11:35 “Hdac8 is a cohesin deacetylase that is required for recycling of cohesion”
        Katsuhiko Shirahige (Univ. Tokyo, Japan)
11:35-12:20 “Association of Condensin with The Chromosome: Mechanism and Its Effect on Transcriptional Silencing”
        Katsuki Johzuka (NIBB, Japan)
12:20-13:30
Lunch & Poster at the Conference Hall
        List of Poster titles
Chair: Katsuhiko Shirahige
13:30-14:15 “Mitotic Chromosome Condensation by Condensin-Dependent Intrachromosomal DNA Interactions”
        Sebastian Heeger (LRI, UK)
14:15-15:00 “A Tale of Two Condensins: Differential Regulation and Concerted Actions”
        Tatsuya Hirano (RIKEN, Japan)
15:00-15:20
Coffee Break
 
Session 4   (mtDNA and cpDNA Dynamics)
Chair: Ľubomír Tomáška
15:20-16:05 “Bases of Break-Induced Replication in Mitochondrial Genome Dynamics”
        Takehiko Shibata (RIKEN, Japan)
16:05-16:50 “Chromosomal DNA Molecules in Mitochondria and Chloroplasts”
        Arnold Bendich (Univ. Washington, USA)
16:50-17:10 Coffee Break
Chair: Takehiko Shibata
17:10-17:55 “Tinkering with Yeast Telomeres”
        Ľubomír Tomáška (Comenius Univ., Slovakia)
18:30
Reception at the Conference Hall
   
October 16 (Sat) at Okazaki Conference Center
Session 5   (Mutation and Gene Evolution)
Chair: Joakim Näsvall
09:00-09:45 “Spontaneous Mutagenesis Associated with Nucleeotide Excision Repair in Escherichia coli.
        Hisaji Maki (NAIST, Japan)
09:45-10:30 “Genome Integrity Preserved by Induction of Apoptosis from DNA Damage”
        Masumi Hidaka (Fukuoka Dental College, Japan)
10:30-10:50
Coffee Break
Chair: Hisaji Maki
10:50-11:35 “DNA Methylation and Heterochromatin Formation in Neurospora Crassa”
        Michael Rountree (Univ.Oregon, USA )
11:35-12:20 “An Experimental Model System for the Evolution of New Genes under Continuous Selection”
        Joakim Näsvall (Uppsala Univ., Sweden)
12:20-12:30 Concluding remarks
        Meng-Chao Yao (IMB, Taiwan)
12:30-13:30
Lunch at the Conference Hall

 

Conference