基礎生物学研究所
| Organizers | Aya Takahashi (NIG) Fumitoshi Ishino (Tokyo Medical and Dental Univ.) Michael Purugganan (New York Univ.) Mitsuyasu Hasebe (NIBB) |
|---|---|
| Venue | Okazaki Conference Center, Okazaki, Japan |
| Date | Mar. 18-23, 2012 |
| Link | OBC8 Website （http://obc.nibb.ac.jp/8th/） |
| Poster |
|
第８回OBCは2007年に開催された第５回OBC「Speciation and Adaptation – Ecological Genetics of Model Organisms and Beyond – 種分化と適応：モデル生物の生態ゲノミクスとその発展」を発展させ、「Speciation and Adaptation – Environment and Epigenetics - 種分化と適応：環境とエピジェネティクス」というテーマで開催された。基生研の主要研究テーマでもある環境に対する生物応答が進化にどのように関連するか、その際に、DNAメチル化、クロマチン修飾、レトロトランスポゾン転移などのエピジェネティックな要因がどう関わりうるのかという問題について、最先端の研究成果と挑戦的な仮説の提唱のもと、OBCが目的とする新分野の開拓を国内外の参加者が活発な討論のもと繰り広げた。本来は、2011年3月開催予定であったが、東日本大震災のため、延期を余儀なくされ、１年後の2012年3月に開催された。しかし、1年の開催延期は参加者に、より充実したデータを生み出す時間を提供することとなり、災いを転じてより大きな成果をあげることができた。 討議内容は、「適応と自然変異におけるメジャーとマイナーQTLの役割」、「自然集団における解析の必要性」、「ショウジョウバエを中心とした種分化を担う遺伝子やその自然集団での多型に関する研究」、「世代を超えた多型維持機構と適応的意義」、「大進化とエピジェネティック変異との関連」などについて５日間にわたり７セッションが開催された。進化学、発生学、生態学が融合して、所謂、EcoEvoDevoとして発露しつつある分野であり、これまで異なったフィールドで研究してきた最先端研究者が一同に集まることで、従来の自分の研究領域を超え、他の研究領域の存在を認識する機会になり、寝食を共にすることで、極めて活発な討論が行われ、今後の新しい生物学分野を切り開くというOBCの目的にかなった会議であった。（長谷部 光泰）
| March 18 (Sun) at Okazaki New Grand Hotel | |
| 18:00 | Get together |
| March 19 (Mon) at Okazaki Conference Center | |
| 11:00 - 12:00 | Registration |
| 12:00 - 13:00 | Lunch |
| 13:00 - 13:05 |
Welcome Address OKADA, Kiyotaka (Director-General, NIBB, Japan) |
| 13:05 - 13:15 |
Opening Remarks TAKAHASHI, Aya (NIG, Japan) |
| Session1 Ecological Genomics | |
| Chair: PURUGGANAN, Michael D. | |
| 13:15 - 14:00 |
Keynote Lecture “Rare and Common Variants and the Multivariate Evolutionary Architecture of Disease” GIBSON, Greg (Georgia Inst. of Tech., USA) |
| 14:00 - 14:20 | Coffee Break |
| Chair: GRESHAM, David | |
| 14:20 - 14:55 |
“Ecological and Evolutionary Functional Genomics: Past, Present, and Future” FEDER, Martin E. (The Univ. of Chicago, USA) |
| 14:55 - 15:15 |
“Multiple Capacitors for Natural Genetic Variation in Wing Shape of Drosophila melanogaster” TAKAHASHI, Kazuo (Okayama Univ., Japan) |
| 15:15 - 15:35 |
“Genetic and Epigenetic Variations in a Natural Plant Population” ARAKI, Kiwako (Kyoto Univ., Japan) |
| 15:35 - 15:55 | Coffee Break |
| Chair: SHIMIZU, Kentaro | |
| 15:55 - 16:30 |
“Evolutionary Genomics of Flowering Gene Networks in Arabidopsis thaliana” HANZAWA, Yoshie (Univ. of Illinois, USA) |
| 16:30 - 17:05 |
“Transcriptional Reprogramming of Metabolism in Plants in Response to Global Environmental Change” LEAKEY, Andrew (Univ. of Illinois, USA) |
| 17:05 - 17:40 |
“Global Gene Expression of Arabidopsis thaliana in the Field” PURUGGANAN, Michael D. (New York Univ., USA) |
| Chair: FEDER, Martin E. | |
| 17:40 - 18:10 | Discussion |
| 18:10 - 20:00 | Dinner at OCC with 3-min talks by poster-only presenters |
| March 20 (Tue) at Okazaki Conference Center | |
| Session2 Evolutionary Genomics and Adaptation I | |
| Chair: AKASHI, Hiroshi | |
| 09:00 - 09:45 |
Keynote Lecture “Population Genomics of Adaptation in Sexual Species” STEPHAN, Wolfgang (LMU Munich, Germany) |
| 09:45 - 10:05 | Coffee Break |
| Chair: STEPHAN, Wolfgang | |
| 10:05 - 10:40 |
“Gene Expression and Protein Evolution in Drosophila” AKASHI, Hiroshi (NIG, Japan) |
| 10:40 - 11:15 |
“Evolutionary Role of Bacterial Homologous Recombination” INNAN, Hideki (SOKENDAI, Japan) |
| 11:15 - 11:35 |
“Compensatory Evolution between Mitochondrial and Nuclear Genomes” OSADA, Naoki (NIG, Japan) |
| 11:35 - 13:30 | Lunch & Poster session (Posterlist PDF165KB) |
| Session3 Evolutionary Genomics and Adaptation II | |
| Chair: COMAI, Luca | |
| 13:30 - 14:05 |
“Toward Recurrent Patterns in the Evolution of Breeding Systems and Polyploid Speciation in Arabidopsis Relatives:” SHIMIZU, Kentaro (Univ. of Zurich, Switzerland) |
| 14:05 - 14:40 |
“Tracing the Origins of Adaptive Variation in Clover” OLSEN, Kenneth M. (Washington Univ., USA) |
| 14:40 - 15:00 |
“Altitudinal Adaptation of Arabidopsis kamchatica: Demography, Physiology and Genes” TANAKA, Kenta (Univ. of Tsukuba, Japan) |
| 15:00 - 15:20 | Coffee Break |
| Chair: Greg Gibson | |
| 15:20 - 15:40 |
“Sequence Conservation Predicts Conserved Developmental Roles for De-ubiquitinases but not Ubiquitin Ligases” NEWFELD, Stuart J. (Arizona State Univ., USA) |
| 15:40 - 16:15 |
“The Functional Basis of Adaptive Evolution in Resource-limited Environments” GRESHAM, David (New York Univ., USA) |
| 16:15 - 16:50 |
“Color Vision Polymorphism in Wild New World Monkeys and Adaptive Significance of Primate Color Vision” KAWAMURA, Shoji (The Univ. of Tokyo, Japan) |
| Chair: OLSEN, Kenneth M. | |
| 16:50 - 17:10 | Discussion |
| 17:10 - 18:00 | Bus to restaurnt |
| 18:00 | Dinner at a Japanese buffet restaurant |
| 19:30 | A view of everyday life of Japan (visit to a shopping mall) |
| March 21 (Wed) at Okazaki Conference Center | |
| Session4 Genetics and Genomics of Speciation | |
| Chair: TAKAHASHI, Aya | |
| 09:00 - 09:35 |
“Genomics of Complex Speciation in the Drosophila simulans Clade, and the Genetic Control of an Evolved Species Difference in the Rate of Crossing Over” PRESGRAVES, Daven (Univ. of Rochester, USA) |
| 09:35 - 10:10 |
“Genetics of Hybrid Inviability and Sterility between Drosophila melanogaster andDrosophila simulans” SAWAMURA, Kyoichi (Univ. of Tsukuba, Japan) |
| 10:10 - 10:45 |
“Neo-Sex Chromosome Formation and Speciation in the Japanese Sticklebacks” KITANO, Jun (NIG, Japan) |
| 10:45 - 11:00 | Coffee Break |
| Chair: SHIMIZU, Kentaro | |
| 11:00 - 11:35 |
“Mechanisms of Arabidopsis Adaptation to Allopolyploidy” COMAI, Luca (UC Davis, USA) |
| 11:35 - 11:55 |
“Molecular Characterization of Pollen Tube Guidance and Its Species-specificity inTorenia” KANAOKA, Masahiro (Nagoya Univ., Japan) |
| 11:55 - 12:30 |
“Association between Color and Behavior due to Expression Variants of a Pleiotropic Gene, ebony, in Drosophila” TAKAHASHI, Aya (NIG, Japan) |
| Chair: PRESGRAVES, Daven | |
| 12:30-12:45 | Discussion |
| 12:45-13:00 | Group Photo |
| 13:00-18:00 | Lunch and Excursion |
| 18:00 | Dinner at a Japanese pub |
| March 22 (Thu) at Okazaki Conference Center | |
| Session5 Epigenetics in Development and Its Transgenerational Effects I | |
| Chair: HASEBE, Mitsuyasu | |
| 09:00 - 09:45 | Keynote Lecture |
|
“Genetics of DNA Methylation in Genes and Transposons in Arabidopsis” KAKUTANI, Tetsuji (NIG, Japan) |
|
| 09:45 - 10:05 | Coffee Break |
| Chair: OKADA, Norihiro | |
| 10:05 - 10:40 |
“The Effects of Maternal Ethanol Consumption on Offspring Epigenotype and Phenotype in the Mouse” CHONG, Suyinn (Qeensland Inst. of Medical Research, Australia) |
| 10:40 - 11:15 |
“Environmental Signals and Epigenetic Changes: from Disease Etiology to Evolution” GUERRERO-BOSAGNA, Carlos (Washington State Univ., USA) |
| 11:15 - 11:35 | Coffee Break |
| Chair: KAKUTANI, Tetsuji | |
| 11:35 - 11:55 |
“Epigenetic Regulation of Somatic Cell Cloning and Embryo Manipulation” KOHDA, Takashi (Tokyo Medical and Dental Univ., Japan) |
| 11:55 - 12:30 |
“Role of ATF-2 Family Transcription Factors in Inheritance of Epigenetic Change Induced by Stress” ISHII, Shunsuke (RIKEN Tsukuba Inst., Japan) |
| 12:30 - 13:30 | Lunch |
| Session6 Epigenetics in Development and Its Transgenerational Effects II | |
| Chair: TAMADA, Yosuke | |
| 13:30 - 14:05 |
“Multigenerational Epigenetic Variation: An Epigenomics and Quantitative Genetics Perspective” COLOT, Vincent (IBENS, France) |
| 14:05 - 14:40 |
“Epigenetic Control of Species Hybridization in Plant Endosperm” KINOSHITA, Tetsu (NAIST, Japan) |
| 14:40 - 15:15 |
“Evolution of the Developmental Functions of Histone Methylations in Land Plants” TAMADA, Yosuke (NIBB, Japan) |
| 15:15 - 15:35 | Coffee Break |
| Chair: COLOT, Vincent | |
| 15:35 - 16:10 |
“The Effects of a Stress-activated Transposon on Arabidopsis Genome” ITO, Hidetaka (Hokkaido Univ., Japan) |
| 16:10 - 16:30 |
“Environmental Stresses Trigger Heritable Changes in the Embryonic mRNA Profile of the Nematode C. elegans” SCHOTT, Daniel (Harvard Univ., USA) |
| 16:30 - 16:50 |
“RPL1, A Gene Regulating Epigenetic Processes Plays a Positive Role in Maintenance of Rice Phenotypic Stability” ZHANG, Cuicui (Huazhong Agricultural Univ., China) |
| Chair: ISHII, Shunsuke | |
| 16:50 - 17:20 | Discussion |
| 17:20 - 18:50 | Poster session with snacks (Posterlist PDF165KB) |
| 19:00 | Reception at a Japanese restaurant |
| March 23 (Fri) at Okazaki Conference Center | |
| Session7 Evolution of Developmental systems | |
| Chair: ISHINO, Fumitoshi | |
| 09:00 - 09:45 | Keynote Lecture |
|
“Evolution of Dosage Compensation and Mammalian X Chromosome Inactivation” GRAVES, Jennifer (La Trobe Univ., Australia) |
|
| 09:45 - 10:05 | Coffee Break |
| Chair: GRAVES, Jennifer | |
| 10:05 - 10:40 |
“Evolution of Genomic Imprinting in Marsupials” RENFREE, Marilyn B. (The Univ. of Melbourne, Australia) |
| 10:40 - 11:15 |
“Contribution of Retrotransposons to Evolution of Genomic Imprinting and Placentation in Mammals” ISHINO, Fumitoshi (Tokyo Medical and Dental Univ., Japan) |
| 11:15 - 11:50 |
“Emergence of Mammals by Emergency: Exaptation” OKADA, Norihiro (Tokyo Inst. of Tech., Japan) |
| 11:50 - 12:10 |
“Endogenous Retroviral-like Aspartic Protease, SASPase as a Key Modulator of Skin Moisturization” MATSUI, Takeshi (Kyoto Univ., Japan) |
| 12:10 - 13:30 | Lunch |
| Chair: RENFREE, Marilyn B. | |
| 13:30 - 14:05 |
“L1 Retrotransposition in Neurons is Modulated by MeCP2” MUOTRI, Alysson (UC San Diego, USA) |
| 14:05 - 14:25 |
“Environmental Activation of Retroelements During Adult Neurogenesis” KUWABARA, Tomoko (AIST, Japan) |
| 14:25 - 15:00 |
“Robust Seasonal Control of a Flowering-time Gene ‘in Natura’” KUDOH, Hiroshi (Kyoto Univ., Japan) |
| Chair: ISHINO, Fumitoshi | |
| 15:00 - 15:30 | Discussion |
| 15:30 - 15:50 |
Closing Remarks PURUGGANAN, Michael D. (New York Univ., USA ) |
