研究概要

RESEARCH: Molecular mechanisms to change differentiated cells to stem cells (8) Role of ING in stem cell formation

Dr. Akihiro Imai (Hiroshima Institute of Technology) in collaboration with Dr. Minoru Kubo (NAIST)

We found that INHIBITOR OF GROWTH (ING) proteins are involved in the change from leaf cells to chloronema apical stem cells in a dissected Physcomitrella leaf. The ING proteins are known to regulate an apoptosis pathway in animals. However, plants do not have the corresponding apoptotic pathway. What is the role of INGs in plants? We are investigating their molecular functions in plant stem cell formation.

  1. Function of STEMIN, whose induction changes differentiated cells to stem cells
  2. Epigenetic regulation during stem cell formation
  3. Role of auxin in stem cell formation
  4. Common factor for stem cell formation between animals and plants
  5. A factor to connect light and wounding signals in stem cell formation
  6. A role of histone chaperon HIRA in stem cell formation
  7. Role of ING in stem cell formation
  8. Cell cycle reentry from the late S or G2 phase
  9. Role of epigenetic regulation in stem cell formation