研究概要

RESEARCH: Molecular mechanisms to change differentiated cells to stem cells (2) Epigenetic regulation during stem cell formation

Assist. Prof. Yosuke Tamada, Assoc. Prof. Takashi Murata
Graduate students are welcome to join.

When a leaf of Physcomitrella is dissected, leaf cells facing the cut change to chloronema apical stem cells. We are interested in observing epigenetic changes including histone modificaiton and DNA methylation in situ in a single cell with inventing microscopy with adaptive optics.

  1. Function of STEMIN, whose induction changes differentiated cells to stem cells
  2. Epigenetic regulation during stem cell formation
  3. Role of auxin in stem cell formation
  4. Common factor for stem cell formation between animals and plants
  5. A factor to connect light and wounding signals in stem cell formation
  6. A role of histone chaperon HIRA in stem cell formation
  7. Role of ING in stem cell formation
  8. Cell cycle reentry from the late S or G2 phase
  9. Role of epigenetic regulation in stem cell formation