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National Institutes of Natural Sciences

National Institute for Basic Biology

International Cooperation

Princeton University - Symposium

The 2nd NIBB - Princeton Symposium "Imaging and Quantitative Biology"

Organizers Michael S. Levine (Princeton Univ.), Danelle Devenport (Princeton Univ.), Kazuhiro Aoki (NIBB), Naoto Ueno (NIBB)
Venue Okazaki Conference Center
Date Oct. 28 – Oct. 30, 2019
Link Symposium website (http://www.nibb.ac.jp/nibb_princeton2/)
Poster

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 The second NIBB-Princeton Joint Symposium entitled 'Imaging and Quantitative Biology' was held on October 28-30th, 2019 at the Okazaki Conference Center. The National Institutes for Natural Sciences (NINS) and Princeton University have been conducting academic exchange and collaborative research in the life sciences based on an academic cooperation agreement that had been signed by these two parties in 2010.
 This NIBB symposium was jointly organized not only with Princeton University, but also with the Division of Quantitative and Imaging Biology (QIB) at the International Research Collaboration Center (IRCC), NINS, the National Institute for Physiological Science (NIPS), the Institute for Molecular Science (IMS), and the Exploratory Research Center on Life and Living Systems (ExCELLS), and was supported by the Advanced Bioimaging Platform (ABiS).
 Although the scientific sessions covered a rather broad spectrum of biological phenomena such as molecular dynamics, cell biology, embryogenesis, symbiosis between organisms and viral infection, and information processing within the brain, the key concept ‘Imaging and Quantitative Biology’ was underlying all the presentations. The latest methodologies such as state of the art imaging technologies, optogenetics, single cell sequencing, mass spectrometry, liquid-liquid phase separation and machine learning presented in the symposium were indeed a showcase of the recent technical advances in the life sciences.
 Eighty-five participants, who were researchers from the various institutes and research centers of NINS, as well as those from other universities enjoyed lively discussions during poster presentations over the three days. In particular, four professors from Princeton University gave insightful comments to the presenters and led the discussions.
 We would like to note that the success of the symposium is something that proves the significant progress of the collaboration between NINS and Princeton University up until now. In closing, we would like to express our gratitude to all participants for taking part in a variety of active discussions, and the IRCC-QIB, the Office of International Cooperation and the individuals from the organizer’s laboratories for coordinating and cooperating with this symposium.

Kazuyoshi Aoki, Naoto Ueno
Organizers

 

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Program
Program  
October 28th (Mon) at the Okazaki Conference Center (OCC)
9:00 - 10:00 Registration
   
Opening Remarks 
10:00 - 10:15 Naoto Ueno (NIBB/IRCC-QIB, Japan)
   
Session 1: Imaging & Optogenetics  Chair: Kazuhiro Aoki
10:15 - 10:45 "Optogenetics for cracking the cell signaling code"
  Jared E. Toettcher (Princeton Univ., USA)
   
10:45 - 11:15 "Visualization and manipulation of cell signaling"
  Kazuhiro Aoki (NIBB/ExCELLS/IRCC-QIB, Japan)
   
11:15 - 11:45 "Multi-photon microscopy innovated by cutting-edge light technologies"
  Tomomi Nemoto (NIPS/ExCELLS, Japan)
   
11:45 - 12:15 "Visualizing the role of boundary elements in enhancer-promoter communication"
  Takashi Fukaya (Univ. Tokyo, Japan)
   
12:15 - 12:30 Group Photograph
   
12:30 - 13:45 Lunch
   
Session 2: Single-Cell/Single-Molecular Imaging  Chair: Ryota Iino
13:45 - 14:15 "3D Multi-Resolution Imaging"
  Haw Yang (Princeton Univ., USA)
   
14:15 - 14:45 "Single-molecule dynamics of motor proteins visualized by plasmonic nanoprobes"
  Ryota Iino (IMS/IRCC-QIB, Japan)
   
14:45 - 15:15 "Imaging of Single-Molecule Dynamics using High-Speed Atomic Force Microscopy"
  Takayuki Uchihashi (ExCELLS/Nagoya Univ., Japan)
   
15:15 - 15:45 Coffee Break
   
Session 3: Pattern Formation  Chair: Michael S. Levine
15:45 - 16:15 "Live imaging of gravity sensing cells"
  Miyo T. Morita (NIBB, Japan)
   
16:15 - 16:45 "Toggle Switch Model for Transcriptional Enhancers"
  Michael S. Levine (Princeton Univ., USA)
   
16:45 - 17:15 "3D morphogenesis of adult appendages from the Folded Epithelial Sheets in Drosophila "
  Shizue Ohsawa (Nagoya Univ., Japan)
   
17:15 - 17:45 Poster Session
   
18:00 - 20:00 Reception along with Poster Session
   
October 29th (Tue) at the Okazaki Conference Center (OCC)
Session 4: Organogenesis  Chair: Shinji Takada
09:30 - 10:00 "Visualization and quantification of Wnt proteins in embryos"
  Shinji Takada (NIBB/ExCELLS, Japan)
   
10:00 - 10:15 "Mechanical force activates FGFR/Erk2 signaling to regulate epithelial tissue integrity in early Xenopus embryos"
  Noriyuki Kinoshita (NIBB, Japan)
   
10:15 - 10:45 Coffee Break
   
10:45 - 11:15 "Establishment of morphological and functional polarity in the mouse oviduct"
  Toshihiko Fujimori (NIBB, Japan)
   
11:15 - 11:45 "Mitogen competition regulates spermatogenic stem cell homeostasis in an open niche"
  Yu Kitadate (NIBB, Japan)
   
11:30 - 13:30 Lunch along with Poster Session
   
After  Lunch Free time
   
October 30th (Wed) at the Okazaki Conference Center (OCC)
Session 5: Symbiosis & Infection  Chair: Shuji Shigenobu
09:00 - 09:30 "Root nodule symbiosis integrated into regulatory systems of host legumes"
  Takashi Soyano (NIBB, Japan)
   
09:30 - 10:00 "Dynamic Organelle Shape and Function in the Context of Viral Infections"
  Ileana Cristea (Princeton Univ., USA)
   
10:00 - 10:30 "Genomic revelations of a mutualism: aphids and the endosymbiont"
  Shuji Shigenobu (NIBB, Japan)
   
10:30 - 10:45 "Adaptation of corals to future warm environments"
  Shunichi Takahashi (NIBB, Japan)
   
10:45 - 11:15 Coffee Break
   
Session 6: Neurobiology  Chair: Nobuyuki Shiina
11:15 - 11:35 "Quantitative assessment of brain transcriptome dynamics in primate neuropsychiatric disease model"
  Yasuhiro Go (NIPS/ExCELLS, Japan)
   
11:35 - 11:55 "Regulation of the dynamics of RNA granule condensates and its implications for long-term memory"
  Nobuyuki Shiina (NIBB/ExCELLS, Japan)
   
11:55 - 12:15 "Whole-brain activity patterns decoded by regional fine-grained activity patterns"
  Junichi Chikazoe (NIPS, Japan)
   
Closing Remarks 
12:15 - 12:20 Ileana Cristea (Princeton Univ., USA)