The Research Enhancement Strategy Office (RESO) was established in 2013 to manage the NIBB action plans proposed by the Director and the Advisory Committee for Programming and Management as an Inter-University Research Institute: (1) promoting internationally top-notch research and (2) providing opportunities for cutting-edge researchers throughout Japan to gather and engage in activities aimed at exploring future academic fields and creating new principles. RESO is composed of six groups with the following missions: (1) planning and evaluation, (2) joint utilization of NIBB facilities and joint research between NIBB members and researchers throughout the world, (3) domestic and international cooperation, (4) promotion of the diversity and education of young researchers, (5) dissemination of information and enhancement of public relations, and (6) collaboration between academia and industry. RESO is mainly managed by University Research Administrators who hold PhDs and have experience in both research and management. RESO cooperates with the mother institute NINS’s Research Enhancement Promotion Headquarters. The activities of this office are partly supported by the Program for Promoting the Enhancement of Research Universities of the Ministry of Education, Culture, Sports, Science and Technology.