日本語

National Institutes of Natural Sciences

National Institute for Basic Biology

International Cooperation

EMBL - Symposium

" Systems Biology and Functional Genomics Workshop "

Organizers Luis Serrano (CRG)
Eileen Furlong (EMBL Heidelberg)
Naoto Ueno (NIBB)
Atsushi Mochizuki (NIBB)
Date Apr. 18-19, 2008

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 Center for Genomic Regulation (CRG) is located at the Barcelona Biomedical Research Park (PRBB), one of the largest research clusters in southern Europe. This meeting was held at the new CRG/PRBB building overlooking the beautiful Catalonian coast. The main purpose of the meeting was to bring Japanese and European scientists in the field together to grasp the current status of systems biology and functional genomics, and to discuss the future direction of the field. We also aimed to stimulate international collaborations between scientists. The meeting included excellent presentations on gene and protein networks, biological systems controlling higher-order phenomena such as complex morphogenesis of organs of animals and plants, and gene regulatory networking of circadian rhythm. As a result of the meeting we realized some key issues that need to be addressed are the setting-up of experimental systems by which data with minimum noise can be obtained, comprehensive collection of data sets with different conditions or genetic backgrounds, a well-designed presentation of data that allows the extraction of biological significance, and the necessity of mathematical modeling to predict the principles behind biological phenomena. There is an ever increasing amount of biological data being accumulated by the achievements of large-scale biology such as genomic, proteomics, and phenomics, and therefore we certainly need sophisticated “Systems Biology”to make the best use of them.

Program
April 18 (Friday)
9:00 James SHARPE (CRG)
"Towards a 4D computer simulation of vertebrate limb development"
9:30 Kazuki HORIKAWA (Hokkaido University)
"Biological pattern formation assisted with coupled oscillator system"
10:00 Rob RUSSELL (EMBL)
"Protein interaction networks"
10:30 coffee-break
11:00 Jochen WITTBRODT (EMBL)
"CRM prediction across metazoans"
11:30 Paola OLIVERI (UCL)
"Global regulatory logic for specification of an embryonic cell lineage"
12:00 Takashi MIURA (Kyoto University)
"Modelling lung branching morphogenesis"
12:30 Eileen FURLONG (EMBL)
"The Dynamics of regulatory networks during development"
13:00 lunch
14:30 Shuji ISHIHARA (University of Tokyo)
"Competitive molecular localization by mass-conserved reaction-diffusion systems"
15:00 Lars HUFNAGEL (EMBL)
"Regulation of Growth during Development: Role of Mechanics"
15:30 Francois NEDELEC (EMBL)
"A model for spindle movements leading to asymmetric division in the C.elegans embryo"
16:00 coffee-break
16:30 Ivan PAPONOV (University of Freiburg)
"Chemical genetics approach to resolve the auxin signalling network"
17:00 Patrick LEMAIRE (IBDM)
"Of gene regulatory networks and cell shapes in the ascidian Ciona intestinalis"
17:30 Takashi ITO (University of Tokyo)
"Unexpected complexity of the budding yeast transcriptome"
April 19 (Saturday)
10:00 Lars STEINMETZ (EMBL)
"High-resolution mapping of meiotic recombination in yeast"
10:30 Shinya KURODA (University of Tokyo) 
"Temporal coding of ERK signaling networks"
11:00 coffee-break
11:30 Mark ISALAN (CRG)
"Engineering rewired bacterial gene networks"
12:00 Shuji SHIGENOBU (NIBB)
"The symbiotic system between insect and endocelluar bacteria"
12:30 Yutaka SATOU (Kyoto University)
"Gene regulatory networks in the Ciona embryo"
13:00 lunch
14:30 Hiroki UEDA (RIKEN, CDB)
"Systems Biology of Mammalian Circadian Clocks"
15:00 Ben LEHNER (CRG)
"When is too much bad for you?"
15:30 Atsushi MOCHIZUKI (NIBB)
"Structure of regulatory networks and diversity of gene expressions"