新学術領域研究「動的クロマチン構造と機能」

研究成果

1.Kajitani T, Kato H, Chikashige Y, Tsutsumi C, Hiraoka Y, Kimura H, Ohkawa Y, Obuse C, Hermand D, Murakami Y
Ser7 of RNAPII-CTD facilitates heterochromatin formation by linking ncRNA to RNAi.
PNAS., 2017 Dec 26;114(52):E11208-E11217. doi: 10.1073/pnas.1714579115. Epub 2017 Dec 13.
Pubmed ID: 29237752

2.Iwamoto M, Osakada H, Mori C, Fukuda Y, Nagao K, Obuse C, Hiraoka Y, Haraguchi T.

Compositionally distinct nuclear pore complexes of functionally distinct dimorphic nuclei in ciliate Tetrahymena.

J. Cell Sci.,2017

Pubmed ID: 28386019

3. Tsujii, A., Miyamoto, Y., Moriyama, T., Tsuchiya, Y., Obuse, C., Mizuguchi, K., Oka, M.*, and Yoneda, Y.*

Retinoblastoma-binding Protein 4-regulated Classical Nuclear Transport Is Involved in Cellular Senescence

J Biol Chem 290, 29375-29388, 2015

Pubmed ID: 26491019

4. Kimoto, C., Moriyama, T., Tsujii, A., Igarashi, Y., Obuse, C., Miyamoto, Y., Oka, M., and Yoneda, Y.

Functional characterization of importin alpha8 as a classical nuclear localization signal receptor

Biochim Biophys Acta 1853, 2676-2683, 2015

Pubmed ID: 26220098

5. Moriyama, T., Sangel, P., Yamaguchi, H., Obuse, C., Miyamoto, Y., Oka, M., and Yoneda, Y.

Identification and characterization of a nuclear localization signal of TRIM28 that overlaps with the HP1 box

Biochem Biophys Res Commun 462, 201-207, 2015

Pubmed ID: 25960296

6. Hayashi-Takanaka, Y., Maehara, K., Harada, A., Umehara, T., Yokoyama, S., Obuse, C., Ohkawa, Y., Nozaki, N., and Kimura, H.

Distribution of histone H4 modifications as revealed by a panel of specific monoclonal antibodies

Chromosome Res ,2015

(web: http://link.springer.com/article/10.1007/s10577-015-9486-4 )

7. Perpelescu, M., Hori, T., Toyoda, A., Misu, S., Monma, N., Ikeo, K., Obuse, C., Fujiyama, A., and Fukagawa, T.

HJURP is involved in the expansion of centromeric chromatin

Mol Biol Cell 26, 2742-2754, 2015

Pubmed ID: 26063729

8. Tanaka, Y., Umata, T., Okamoto, K., Obuse, C., and Tsuneoka, M.

CxxC-ZF domain is needed for KDM2A to demethylate histone in rDNA promoter in response to starvation

Cell Struct Funct 39, 79-92, 2014

Pubmed ID: 24553073

9. Suzuki, S., Nagao, K., Obuse, C., Murakami, Y., and Takahata, S.

A novel method for purification of the endogenously expressed fission yeast Set2 complex

Protein Expr Purif 97, 44-49, 2014

Pubmed ID: 24583182

10. Saito, N., Qiao, H., Yanagi, T., Shinkuma, S., Nishimura, K., Suto, A., Fujita, Y., Suzuki, S., Nomura, T., Nakamura, H., Nagao, K., Obuse, C., Shimizu, H., and Abe, R.

An annexin A1-FPR1 interaction contributes to necroptosis of keratinocytes in severe cutaneous adverse drug reactions

Sci Transl Med 6, 245ra295, 2014

Pubmed ID: 25031270

11. Sato, Y., Mukai, M., Ueda, J., Muraki, M., Stasevich, T. J., Horikoshi, N., Kujirai, T., Kita, H., Kimura, T., Hira, S., Okada, Y., Hayashi-Takanaka, Y., Obuse, C., Kurumizaka, H., Kawahara, A., Yamagata, K., Nozaki, N., and Kimura, H.

Genetically encoded system to track histone modification in vivo

Sci Rep 3, 2436, 2013

Pubmed ID: 23942372

12. Hoshina, S., Yura, K., Teranishi, H., Kiyasu, N., Tominaga, A., Kadoma, H., Nakatsuka, A., Kunichika, T., Obuse, C., and Waga, S.

Human origin recognition complex binds preferentially to G-quadruplex-preferable RNA and single-stranded DNA

J Biol Chem 288, 30161-30171, 2013

Pubmed ID: 24003239

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