The 62nd NIBB Conference

Force in Development

Program

 

November 17 (Mon) at the Okazaki Conference Center (OCC)
09:00 - 09:20 Registration
   
Opening Remarks  
09:20 - 09:30 Masayuki Yamamoto (Director General, National Institute for Basic Biology, Japan)
   
Plenary 1  
Chair: Naoto Ueno  
09:30 - 10:20 “Interplay of cell dynamics and epithelial tension during morphogenesis of the Drosophial pupal wing” 
  Suzanne Eaton (The Max Planck Institute of Molecular Cell Biology and Genetics, Germany)
   
Session 1: Cellular dynamics during morphogenesis I
Chair: Naoto Ueno  
10:20 - 10:50 “Sequential Contraction and Localized Exchange of Apical Junctions Drives Unidirectional Zippering and Neural Tube Closure in a Simple Chordate” 
  Edwin Munro (University of Chicago, USA)
   
10:50 - 11:10 Coffee Break
   
11:10 - 11:40 “Mechanical stability and instability in epithelial tube morphogenesis”
  Shigeo Hayashi (RIKEN Center for Developmental Biology, Japan)
   
11:40 - 12:10 “Role of spatial pattern of contracting cells in tissue invagination”
  Yasuhiro Inoue (Kyoto University, Japan)
   
12:10 - 12:20 Group Photo
   
12:20 - 13:10 Lunch
   
Session 2: Cellular dynamics during morphogenesis II
Chair: Toshihiko Fujimori and Kenji Matsuno
13:10 - 13:40 “Ca2+ dynamics during neural tube formation of Xenopus”
  Naoto Ueno (National Institute for Basic Biology, Japan)
   
13:40 - 14:00 Short Talk from Poster No. 26
  “Filopodia-Mediated Fibrillar Adhesion and Vascular Constriction Facilitate Patterned Deposition of Fibronectin Pillars that Bridge Somites and the Endoderm”
  Yuki Sato (Kyushu University, Japan)
   
14:00 - 14:30 “Biomechanical control of tissue morphogenesis by GPCR signalling”
  Thomas Lecuit (The Developmental Biology Institute of Marseille, France)
   
14:30 - 14:50 Coffee Break
   
14:50 - 15:20 “Development, validation and applications of Bayesian force/stress inference”
  Kaoru Sugimura (Kyoto University, Japan)
   
15:20 - 15:50 “The mechanical control of epithelial invagination via α-Catenin”
  Yu-Chiun Wang (RIKEN Center for Developmental Biology, Japan)
   
15:50 - 16:10 Short Talk from Poster No. 32
  “Tissue Force Coupling Drives Collective Cell Migration and Large-Scale Tissue Flow in Zebrafish”
  Michael Smutny (Institute of Science and Technology Austria, Austria)
   
16:10 - 16:30 Coffee Break
   
Session 3: Hemodynamics in organogenesis
Chair: Takeo Matsumoto 
16:30 - 17:00 “Hemodynamic Forces as a Regulator of Cardiogenesis and Circulatory Homeostasis”
  Toshihiko Ogura (Tohoku University, Japan)
   
17:00 - 17:30 “Mechanism of hemodynamics sensing during cardiovascular development”
  Julien Vermot (Institut de Génétique et de Biologie Moléculaire et Cellulaire, France)
   
17:30 - 17:50 Short Talk from Poster No. 18
  “Modeling Cell-cell interaction and Random Cell Movement in collective migration of MDCK cells”
  Takashi Miura (Kyushu University, Japan)
   
Poster Session  
18:00 - 20:00  Poster Session & Mixer     Poster Title (PDF 70KB)
   
   
November 18 (Tue) at OCC
Plenary 2  
Chair: Carl-Philipp Heisenberg
09:00 - 09:50 “Embryo-scale integration of tissue mechanics”
  Maria Leptin (European Molecular Biology Laboratory, Germany)
   
Session 4: Symmetry breaking of cell and tissue
Chair: Carl-Philipp Heisenberg
09:50 - 10:20 “Active torque generation by the actomyosin cell cortex for left/right symmetry breaking”
  Stephan W. Grill (Biotechnology Center TU Dresden, Germany)
   
10:20 - 10:50 “Cell Chirality Induces Mechanical Force Driving the Left-Right Directional Rotations of the Gut in Drosophila
  Kenji Matsuno (Osaka University, Japan)
   
10:50 - 11:10 Coffee Break
   
11:10 - 11:40 “PCP Pathway and Cellular Geometric Pattern in Oviduct Morphogenesis”
  Toshihiko Fujimori (National Institute for Basic Biology, Japan)
   
11:40 - 12:10 “Establishment of robust compartments in fish somites along the dorsoventral axis”
  Hiroyuki Takeda (The University of Tokyo, Japan)
   
12:10 - 12:30 Short Talk from Poster No. 23
  “Vertex Model for Simulating Mechanics-Based Multicellular Dynamics in 3D”
  Satoru Okuda (RIKEN Center for Developmental Biology, Japan)
   
12:30 - 13:30 Lunch
   
Session 5: Physical environment of embryos
Chair: Shigeo Hayashi and Takaki Miyata
13:30 - 14:00 “Forces and Regulation of Cell Sheet Morphogenesis During Dorsal Closure in Drosophila”
  Daniel Kiehart (Duke University, USA)
   
14:00 - 14:30 “Biomechanical analyses of Xenopus laevis embryo: Toward estimation of stress and strain distributions during morphogenesis”
  Takeo Matsumoto (Nagoya Institute of Technology, Japan)
   
14:30 - 15:00 “Extracellular ATP and its receptor P2Y2 mediate a closed-loop feedback circuit for the mechanical control of gastrulation”
  Lance Davidson (The University of Pittsburgh, USA)
   
15:00 - 15:20 Coffee Break
   
15:20 - 15:50 “Seeing How Mammalian Life Starts: Quantitative Single-Cell Imaging of Living Embryos”
  Nicolas Plachta (European Molecular Biology Laboratory Australia, Australia)
   
15:50 - 16:10 Short Talk from Poster No. 10
  “Measuring force between cells during development by FRET”
  Yutaro Hori (The University of Tokyo, Japan) and Yusuke Mii (National Institute for Basic Biology, Japan)
   
16:10 - 16:20 Short Break
   
16:20 - 16:50 “Adhesion Disengagement and Maintenance of Tissue Integrity during Apoptosis in Epithelial Tissue”
  Yusuke Toyama (National University of Singapore, Singapore)
   
Plenary 3  
Chair: Takaki Miyata
16:50 - 17:40 “Contact-Dependent Promotion of Cell Movement”
  Masatoshi Takeichi (RIKEN Center for Developmental Biology, Japan)
   
   
November 19 (Wed) at OCC
Session 6: Mechanics in cell migration
Chair: Lance Davidson
09:00 - 09:30 “Nuclear Traffic and Mechanics under High-degree Pseudostratification: Lessons from Mammalian Cerebral Neuroepithelia”
  Takaki Miyata (Nagoya University Graduate School of Medicine, Japan)
   
09:30 - 09:50 Short Talk from Poster No. 24
  “Invasive Migration Of Drosophila Macrophages During Embryogenesis”
  Aparna Ratheesh (The Institute of Science and Technology Austria, Austria)
   
09:50 - 10:10 Short Talk from Poster No. 16
  “Left-right Asymmetric Planar Cell Polarity Controls Directional Collective Cell Migration in Epithelial Morphogenesis”
  Erina Kuranaga (RIKEN Center for Developmental Biology, Japan)
   
10:10 - 10:30 Coffee Break
   
10:30 - 11:00 “Force, Cadherin Adhesions, and the Regulation of Dynamic Cytoskeleton Organization Drives Morphogenetic Collective Cell Migration”
  Gregory Weber (Rutgers, The State University of New Jersey, USA)
   
11:00 - 11:30 “Cortical Contractility Triggers a Motile Switch to Fast Amoeboid Migration in 3D Environments”
  Carl-Philipp Heisenberg (The Institute of Science and Technology Austria, Austria)
   
Closing Remarks
11:30 - 11:40  Hiroyuki Takeda (The University of Tokyo, Japan)