Pernille Rørth (EMBL Heidelberg, Germany)
" Guidance Mechanisms for Invasive Migration of Cell Cluster "
16:30-17:00
Soichi Wakatsuki (KEK, Japan)
" Structural Insights into Ubiquitin Recognition in Intracellular Transport "
17:00-21:00
Mixer and Poster Session
DECEMBER 4, Monday
Session 3-1: Ubiquitin 1 Chair:
Rachel E. Klevit
09:00-09:30
Thomas Sommer (Max-Delbruck-Center for Molecular Medicine, Germany)
" Protein Quality Control by the HRD-Ligase Complex "
09:30-10:00
Kazuhiro Iwai (Osaka City University, Japan)
" Identification of a Ligase Complex Polymerizing Linear Polyubiquitin Chains and Its Physiological Role "
10:00-10:30
David Fushman (University of Maryland, USA)
" Structural Studies of Polyubiquitin Chains: Conformation, Dynamics, and Ligand Binding "
10:30-10:50
Coffee break
10:50-11:20
Shigeaki Kato (The University of Tokyo, Japan)
" Functional Regulation of Nuclear Steroid Hormone Receptors through Protein Degradation "
11:20-11:50
Ivan Dikic (Johann Wolfgang Goethe University, Germany)
" Ubiquitin Signaling Pathways "
11:50-13:10
Lunch
Session 3-2: Ubiquitin 2 Chair:
Kazuhiro Iwai
13:10-13:40
Takumi Kamura (Nagoya University, Japan)
" VHL-Box and SOCS-Box Domains Determine Binding Specificity for Cul2-Rbx1 and Cul5-Rbx2 Modules of Ubiquitin Ligases "
13:40-14:10
Rachel E. Klevit (University of Washington, USA)
" New Insights into the Role and Mechanism of E2 Ubiquitin-Conjugating Enzymes "
14:10-14:40
Kylie J. Walters (University of Minnesota, USA)
" The Interpreters of Ubiquitylation: How Do Ubiquitin Receptor Proteins Deliver Substrates to the Proteasome? "
14:40-15:10
Keiji Tanaka (Rinshoken, Japan)
" Multiple Chaperones Assist the Assembly of Mammalian 20S Proteasomes "
15:10-15:40
Coffee break
Session 4: Mechanism of UBL Conjugation Chair:
Thomas Sommer
15:40-16:10
Brenda A. Schulman (St. Jude Children's Research Hospital, USA)
" Insights into the Specificity of Ubiquitin-Like Protein Transfer Cascades "
16:10-16:40
Christopher D. Lima (Sloan-Kettering Institute, USA)
" Structural Insights into Protein Modification by SUMO "
16:40-17:00
Yoshinori Ohsumi (NIBB, Japan)
" Two Ubiquitin-Like Conjugation Systems Essential for Autophagy "
17:00-17:20
Hitoshi Nakatogawa (NIBB, Japan)
" Membrane Tethering and Fusion Mediated by Atg8, a Ubiquitin-Like Protein Required for Autophagosome Formation "
Session 5: Modification by Lipid & Sugar Chair:
Koichi Kato
09:00-09:30
Akio Kihara (Hokkaido University, Japan)
" Palmitoylation of Sphingosine Kinase and Sphingosine 1-Phosphate Receptor 1 by DHHC Cys-Rich Domain-Containing Palmitoyltransferases "
09:30-10:00
Minoru Yoshida (RIKEN, Japan)
" Protein Lysine Acetylation as a Molecular Modulator for Cellular Functions "
10:00-10:20
Coffee break
10:20-10:50
Roger S. Goody (Max-Planck-Institute for Molecular Physiology, Germany)
" The Mechanistic And Structural Basis of Rab-GTPase Prenylation and Recycling "
10:50-11:20
Tadashi Suzuki (Osaka University, Japan)
" Deglycosylation of Newly Synthesized Glycoproteins by Cytoplasmic Peptide:N-glycanase (PNGase) "
11:20-11:50
Koichi Kato (Nagoya City University, Japan)
" NMR Views of Protein Conjugation with Ubiquitin and Sugar "