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 View Poster of The Fourth NIBB-EMBL Symposium (JPEG 567kb) |
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| December 2 (Sat) | 19:00-20:00 | Registration for Invited Speakers (Okazaki New Grand Hotel) |
| December 3 (Sun) | |
| 08:40- | Registration (Okazaki Conference Center) |
| 09:05-09:10 | Opening Remarks : Yoshitaka Nagahama (Vice President, NIBB, Japan) |
| 09:10-09:50 | Plenary Lecture : Takao Kondo (Nagoya University, Japan) " KaiC as the Primary Pacemaker of Cyanobacterial Circadian Clock " |
| Session 1: SUMO Chair: Christopher D. Lima | |
| 09:50-10:20 | Hisato Saitoh (Kumamoto University, Japan) " Involvement of SUMO-SIM Interaction in MBD1- and MCAF1-Mediated Heterochromatin Formation " |
| 10:20-10:40 | Coffee break |
| 10:40-11:10 | Ken-ichirou Morohashi (NIBB, Japan) " Regulation of Ad4BP/SF-1 by SUMO " |
| 11:10-11:40 | Helle D. Ulrich (Cancer Research UK, UK) " Function of the Ubiquitin System in Replicative DNA Damage Bypass " |
| 11:40-12:10 | Masahiro Shirakawa (Kyoto University, Japan) " Structures of SUMO-1- and SUMO-3- Conjugated Thymine DNA Glycosylase " |
| 12:10-13:30 | Lunch |
| Session 2-1: Membrane Biology 1 Chair: Winfried Weissenhorn | |
| 13:30-14:00 | Simona Polo (IFOM, The FIRC Institute for Molecular Oncology, Milan, Italy) " Molecular Mechanisms of Coupled Monoubiquitination " |
| 14:00-14:30 | Thomas Sommer (Max-Delbruck-Center for Molecular Medicine, Germany) " Protein Quality Control by the HRD-Ligase Complex " |
| 14:30-15:00 | Scott D. Emr (UCSD, USA) " Ubiquitin, PIPs and ESCRTs in Receptor Down-Regulation " |
| 15:00-15:30 | Coffee break |
| Session 2-2: Membrane Biology 2 Chair: Scott D. Emr | |
| 15:30-16:00 | Winfried Weissenhorn (EMBL Grenoble, France) " Structural Biology of Endosomal Vesicle Formation " |
| 16:00-16:30 | Pernille Rørth (EMBL Heidelberg, Germany) " Guidance Mechanisms for Invasive Migration of Cell Cluster " |
| 16:30-17:00 | Soichi Wakatsuki (KEK, Japan) " Structural Insights into Ubiquitin Recognition in Intracellular Transport " |
| 17:00-21:00 | Mixer and Poster Session |
| December 4 (Mon) | |
| Session 3-1: Ubiquitin 1 Chair: Rachel E. Klevit | |
| 09:00-09:30 | Hiroyuki Kawahara (Hokkaido University, Japan) " Proteasomal Ubiquitin Receptor RPN-10 Controls TRA-2-Mediated Sex Determination in Caenorhabditis elegans " |
| 09:30-10:00 | Kazuhiro Iwai (Osaka City University, Japan) " Identification of a Ligase Complex Polymerizing Linear Polyubiquitin Chains and Its Physiological Role " |
| 10:00-10:30 | David Fushman (University of Maryland, USA) " Structural Studies of Polyubiquitin Chains: Conformation, Dynamics, and Ligand Binding " |
| 10:30-10:50 | Coffee break |
| 10:50-11:20 | Shigeaki Kato (The University of Tokyo, Japan) " Functional Regulation of Nuclear Steroid Hormone Receptors through Protein Degradation " |
| 11:20-11:50 | Ivan Dikic (Johann Wolfgang Goethe University, Germany) " Ubiquitin Signaling Pathways " |
| 11:50-13:10 | Lunch |
| Session 3-2: Ubiquitin 2 Chair: Kazuhiro Iwai | |
| 13:10-13:40 | Takumi Kamura (Nagoya University, Japan) " VHL-Box and SOCS-Box Domains Determine Binding Specificity for Cul2-Rbx1 and Cul5-Rbx2 Modules of Ubiquitin Ligases " |
| 13:40-14:10 | Rachel E. Klevit (University of Washington, USA) " New Insights into the Role and Mechanism of E2 Ubiquitin-Conjugating Enzymes " |
| 14:10-14:40 | Kylie J. Walters (University of Minnesota, USA) " The Interpreters of Ubiquitylation: How Do Ubiquitin Receptor Proteins Deliver Substrates to the Proteasome? " |
| 14:40-15:10 | Keiji Tanaka (RINSHOKEN, Japan) " Multiple Chaperones Assist the Assembly of Mammalian 20S Proteasomes " |
| 15:10-15:40 | Coffee break |
| Session 4: Mechanism of UBL Conjugation Chair: Thomas Sommer | |
| 15:40-16:10 | Brenda A. Schulman (St. Jude Children's Research Hospital, USA) " Insights into the Specificity of Ubiquitin-Like Protein Transfer Cascades " |
| 16:10-16:40 | Christopher D. Lima (Sloan-Kettering Institute, USA) " Structural Insights into Protein Modification by SUMO " |
| 16:40-17:00 | Yoshinori Ohsumi (NIBB, Japan) " Two Ubiquitin-Like Conjugation Systems Essential for Autophagy " |
| 17:00-17:20 | Hitoshi Nakatogawa (NIBB, Japan) " Membrane Tethering and Fusion Mediated by Atg8, a Ubiquitin-Like Protein Required for Autophagosome Formation " |
| 17:20-17:50 | Fuyuhiko Inagaki (Hokkaido University, Japan) " Structural Biology of Autophagy " |
| 18:20-21:00 | Social Party at Kikyu |
| December 5 (Tue) | |
| Session 5: Modification by Lipid & Sugar Chair: Koichi Kato | |
| 09:00-09:30 | Akio Kihara (Hokkaido University, Japan) " Palmitoylation of Sphingosine Kinase and Sphingosine 1-Phosphate Receptor 1 by DHHC Cys-Rich Domain-Containing Palmitoyltransferases " |
| 09:30-10:00 | Minoru Yoshida (RIKEN, Japan) " Protein Lysine Acetylation as a Molecular Modulator for Cellular Functions " |
| 10:00-10:20 | Coffee break |
| 10:20-10:50 | Roger S. Goody (Max-Planck-Institute for Molecular Physiology, Germany) " The Mechanistic And Structural Basis of Rab-GTPase Prenylation and Recycling " |
| 10:50-11:20 | Tadashi Suzuki (Osaka University, Japan) " Deglycosylation of Newly Synthesized Glycoproteins by Cytoplasmic Peptide:N-glycanase (PNGase) " |
| 11:20-11:50 | Koichi Kato (Nagoya City University, Japan) " NMR Views of Protein Conjugation with Ubiquitin and Sugar " |
| 11:50-12:00 | Closing Remarks : Yoshinori Ohsumi (NIBB, Japan) |
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