原著論文
Tsuchiya Y, Mii Y, Okada K, Furuse M, Okubo T, Takada S.
Ripply3 is required for the maintenance of epithelial sheets in the morphogenesis of pharyngeal pouches.
【PudMed】
Dev Growth Differ. 2018 Feb 22. doi: 10.1111/dgd.12425
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Mii Y, Yamamoto T, Takada R, Mizumoto S, Matsuyama M, Yamada S, Takada S, Taira M.
Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus.
【PudMed】
Nat Commun. 2017 Dec 7;8(1):1973. doi: 10.1038/s41467-017-02076-0.
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Chen Q, Takada R, Noda C, Kobayashi S, Takada S.
Different populations of Wnt-containing vesicles are individually released from polarized epithelial cells.
【PudMed】
Sci Rep. 2016 Oct 21;6:35562. doi: 10.1038/srep35562.
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Yabe T, Hoshijima K, Yamamoto T, Takada S.
Quadruple zebrafish mutant reveals different roles of Mesp genes in somite segmentation between mouse and zebrafish.
【PudMed】
Development. 2016 Aug 1;143(15):2842-52. doi: 10.1242/dev.133173. Epub 2016 Jul 6.
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Kazunori Okada*, Keiji Inohaya, Takeshi Mise, Akira Kudo, Shinji Takada* and Hiroshi Wada* (* Authors for corresponding)
Reiterative expression of pax1 directs pharyngeal pouch segmentation in medaka.
【PudMed】
Development. 2016 May 15;143(10):1800-10.
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Yabe T, Takada S.
Molecular mechanism for cyclic generation of somites: Lessons from mice and zebrafish.
【PudMed】
Dev Growth Differ. 2016 Jan;58(1):31-42. doi: 10.1111/dgd.12249. Epub 2015 Dec 17.
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Wanglar C, Takahashi J, Yabe T, Takada S.
Tbx protein level critical for clock-mediated somite positioning is regulated through interaction between Tbx and Ripply.
【PudMed】
PLoS One. 2014 Sep 26;9(9):e107928.
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Yabe T, Takada S.
Mesogenin causes embryonic mesoderm progenitors to differentiate during development of zebrafish tail somites.
【PudMed】
Dev. Biol., 2012 Oct, 370(2):213-22.
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Chen Q, Takada R, Takada S.
Loss of Porcupine impairs convergent extension during gastrulation in zebrafish.
【PudMed】
J. Cell Sci., 2012 May, 125(Pt 9):2224-34
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Okubo T, Kawamura A, Takahashi J, Yagi H, Morishima M, Matsuoka R, Takada S.
Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice.
【PudMed】
Development, 2011 Jan, 138(2):339-48.
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Takahashi J, Ohbayashi A, Oginuma M, Saito D, Mochizuki A, Saga Y, Takada S.
Analysis of Ripply1/2-deficient mouse embryos reveals a mechanism underlying the rostro-caudal patterning within a somite.
【PudMed】
Dev. Biol., 2010 Jun, 342(2):134-45.
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Kawamura A, Koshida S, Takada S.
Activator-to-repressor conversion of T-box transcription factors by the Ripply family of Groucho/TLE-associated mediators.
【PudMed】
Mol. Cell Biol., 2008 Mar, 28:3236-3244
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Akanuma T, Koshida S, Kawamura A, Kishimoto Y, Takada S.
Paf1 complex homologes are required for Notch-regulated transcription during somite segmentation.
【PudMed】
EMBO Rep., 2007 Sep, 8:858-863
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Takada R, Satomi Y, Kurata T, Ueno N, Norioka S, Kondoh H, Takao T, Takada S.
Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion.
【PudMed】
Dev. Cell, 2006 Dec, 11:791-801
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Yamaguchi Y, Yonemura S, Takada S.
Grainyhead-related transcription factor is required for duct maturation in the salivary gland and the kidney of the mouse.
【PudMed】
Development, 2006 Dec, 133:4737-4748
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Kawamura A, Koshida S, Hijikata H, Ohbayashi A, Kondoh H, Takada S.
Groucho-associated transcriptional repressor ripply1 is required for proper transition from the presomitic mesoderm to somites.
【PudMed】
Dev. Cell, 2005 Dec, 9:735-744
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Takada R, Hijikata H, Kondoh H, Takada S.
Analysis of combinatorial effects of Wnts and Frizzleds on beta-catenin/armadillo stabilization and Dishevelled phosphorylation.
【PudMed】
Genes to Cells, 2005 Sep, 10:919-928
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Kawamura A*, Koshida S*, Hijikata H, Sakaguchi T, Kondoh H, Takada S.(*eqaulally contributed)
Zebrafish hairy/enhancer of split protein links FGF signaling to cyclic gene expression in the periodic segmentation of somites.
【PudMed】
Genes. Dev., 2005, 19:1156-1161
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Koshida S, Kishimoto Y, Ustumi H, Shimizu T, Furutani-Seiki M, Kondoh H, Takada S.
Integrinalpha5-dependent Fibronectin accumulation for maintenance of somite boundaries in zebrafish embryos.
【PudMed】
Dev. Cell, 2005 Apr, 8:587-589
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Yamaguchi Y, Ogura S, Ishida M, Karasawa M, Takada S.
Gene trap screening as an effective approach for identification of Wnt-responsive genes in the mouse embryo.
【PudMed】
Dev. Dyn., 2005 Jun, 233:484-495
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Muroyama Y, Kondoh H, Takada S.
Wnt proteins promote neuronal differentiation in neural stem cell culture.
【PudMed】
Biochem. Biophys. Res. Commun., 2004 Jan, 313:915-921
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Ohbayashi N, Shibayama M, Kurotaki Y, Imanishi M, Fujimori T, Itoh N, Takada S.
Fgf18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis.
【PudMed】
Genes Dev., 2002, 16:870-879
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Muroyama Y, Fujihara M, Ikeya M, Kondoh H, Takada S.
Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord.
【PudMed】
Genes Dev, 2002, 16:548-553
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Ikeya M, Takada S.
Wnt-3a is required for somite specification along anteroposterior axis of the mouse embryo and regulates cdx-1 expression.
【PudMed】
Mech. Dev., 2001 May, 103:27-33
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Yamaguchi T P*, Takada S*, Yoshikawa Y, Wu N, McMahon A P.(*equal contribution)
T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification.
【PudMed】
Genes Dev., 1999, 13:3185-3190
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Ikeya M, Takada S.
Wnt signaling from the dorsal neural tube is required for the formation of the medial dermomyotome.
【PudMed】
Development, 1998 Dec, 125:4969-4976
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Shibamoto S, Higano K, Takada R, Ito F, Takeichi M, Takada S.
Cytoskeletal reorganization by soluble Wnt-3a protein signaling.
【PudMed】
Genes to Cells, 1998 Oct, 3:659-670
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Yoshikawa Y, Fujimori T, McMahon A P, Takada S.
Evidence that absence of Wnt-3a signaling promotes neuralization instead of paraxial mesoderm development in the mouse.
【PudMed】
Dev. Biol., 1997 Mar, 183:234-242
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Ikeya M, Lee S M, Johnson J E, McMahon A P, Takada S.
Wnt signalling required for expansion of neural crest and CNS progenitors.
【PudMed】
Nature, 1997 Oct, 389:966-970
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Takada S, Stark K L, Shea M J, Vassileva G, McMahon J A, McMahon A P.
Wnt-3a regulates somite and tailbud formation in the mouse embryo.
【PudMed】
Genes Dev., 1994 Jan, 8:174-189
総 説
高田慎治、高田律子
Wntタンパク質の修飾とその意義
実験医学 26，361-366 （2008）
--------------------------------------------------------------------------------
高田律子
分泌性シグナルタンパク質の脂質修飾と、その意義
生化学 79，888-889 （2007）
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高田慎治、高田律子
Wntタンパク質の分泌と濃度勾配形成
細胞工学 26，1153-1156 （2007）
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川村哲規、越田澄人、高田慎治
Groucho結合因子Ripply1による分節プログラムの制御
細胞工学 25，272-273 （2006）
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室山優子、高田慎治
脊髄の初期発生における背側介在神経細胞の発生
細胞工学 21，476-47 .(2002)
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池谷 真、高田慎治
脊椎動物の原腸形成期におけるWntシグナルの役割
細胞工学 19, 1644-1649 (2000)
--------------------------------------------------------------------------------
高田慎治
Wntシグナルによる形態形成とその分子メカニズム
細胞工学 19, 1598-1603 (2000)
--------------------------------------------------------------------------------
高田慎治、山口良文
Wntシグナル伝達
現代化学 増刊37 「シグナル伝達ネットワーク」西田栄介編 pp80-86 (2000)
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高田慎治、池谷 真
脊椎動物の神経管から分泌されるWnt分子と形態形成
生化学 71, 1243-1247 (1999)
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高田慎治
マウス胚発生におけるWnt遺伝子の役割
蛋白質 核酸 酵素 40, 2162-2174 (1995)