July 18th (Wed) at the Okazaki Conference Center (OCC)
The 60th NIBB Conference
Opening Remarks
09:00 - 09:10
Kiyotaka Okada (Director-General of the National Institute for Basic Biology, Japan)
09:10 - 09:20
Satoru Kobayashi & Shosei Yoshida (National Institute for Basic Biology, Japan)
Special Lectures
Mark Van Doren, Satoru Kobayashi
09:20 - 10:20
“Silencing the Germline”
Ruth Lehmann (New York University, USA)
10:20 - 10:30
Coffee Break
10:30 - 11:30
“Development in vivo of Fertilization-Competent Oocyte-like Cells in the Absence of Meiotic Initiation or Prophase”
David C Page (Whitehead Institute for Biomedical Research, USA)
11:30 - 13:00
Lunch Break
Session I
Regulatory Mechanism of Germline Specification
Akira Nakamura, Geraldine Seydoux
13:00 - 13:40
“RNA Silencing in Germline Stem Cells”
Geraldine Seydoux (Johns Hopkins University, USA)
13:40 - 14:20
“Germline Transcriptional Repression in Drosophila and Ciona Embryos”
Akira Nakamura (RIKEN Center for Developmental Biology, Japan)
14:20 - 14:40
Coffee Break
14:40 - 15:20
“PEM, a Localized Maternal Factor Unique to Ascidians, Represses Germline Gene Expression through RNAP II Regulation and Binding to p-TEFb”
Gaku Kumano (Osaka University, Japan)
15:20 - 16:00
“Mechanism and Reconstitution In Vitro of Germ Cell Specification in Mice”
Mitinori Saitou (Kyoto University, Japan)
16:00 - 16:30
Coffee Break
Short Talks I
Yasuhisa Matsui, Mitinori Saitou
16:30 - 16:45
“Primordial Germ Cells Transmigrate from Blood Stream to Gonad in Avian Embryos: Novel Behavior Revealed by Live-imaging Analyses”
Daisuke Saito (Nara Institute of Science and Technology, Japan)
16:45 - 17:00
“PRDM14 Promotes Active DNA Demethylation through the Base Excision Repair Pathway in Embryonic Stem Cells”
Yoshiyuki Seki (Kwansei Gakuin University, Japan)
17:00 - 17:15
“NANOS2-mediated RNA Regulation in the Differentiation of Mouse Male Gonocytes”
Atsushi Suzuki (Yokohama National University, Japan)
17:15 - 17:35
Coffee Break
17:35 - 17:50
“Independent Evolution of Sex Chromosomes through Recurrent Use of Sox3 in Medaka Fish and Mammals”
Yusuke Takehana (National Institute for Basic Biology, Japan)
17:50 - 18:05
“Effect of Fetal Leydig Cell-Specific Ad4BP/SF-1 Gene Disruption on Masculinization and Spermatogenesis”
Yuichi Shima (Kyushu University, Japan)
18:05 - 18:20
“Y Chromosomal Azoospermic Factor RBMY and Estrogen Signaling Coordinately Regulate Male-specific Alternative Splicing”
Matomo Sakari (University of Tokushima, Japan)
18:20 - 18:35
“The Germ Plasm-dependent and -independent Mechanisms for the Germ Cell Specification in the Ascidian, C. intestinalis”
Maki Shirae-Kurabayashi (Hiroshima University, Japan)
19:00 - 21:00
Mixer
July 19th (Thu) at OCC
The 60th NIBB Conference
Session II
Regulatory Mechanism of Germline Sex
Mark Van Doren, Peter Koopman
09:00 - 09:40
“Sexual Dimorphism in the Gonad Stem Cell Niche”
Mark Van Doren (Johns Hopkins University, USA)
09:40 - 10:20
“Mechanism Regulating Germline Sexual Identity in Drosophila Embryos” Satoru Kobayashi (National Institute for Basic Biology, Japan)
10:20 - 10:40
Coffee Break
10:40 - 11:20
“Molecules That Maintain and Regulate Germ Cells during Sexual Differentiation of Medaka Gonads”
Minoru Tanaka (National Institute for Basic Biology, Japan)
11:20 - 12:00
“Factors Influencing the Sex-specific Differentiation of Fetal Germ Cells”
Peter Koopman (The University of Queensland, Australia)
12:00 - 12:40
“Genetic Pathways Leading to Sexual Fate Decision in Mouse Germ Cells”
Yumiko Saga (National Institute of Genetics, Japan)
“Max is a Repressor of Germ-cell-related Gene Expression in Mouse
Embryonic Stem Cells”
Yasuhisa Matsui (Tohoku University, Japan)
16:10 - 16:50
“Sex-inducing Effects by ‘Feeding’: Switching from Asexual to Sexual Reproduction in the Planarian Dugesia ryukyuensis”
Kazuya Kobayashi (Hirosaki University, Japan)
16:50 - 17:30
“Germ Cell Development and Regeneration in Planarians:Implications for Understanding Parasitic Flatworms”
Phillip A Newmark (University of Illinois, USA)
17:30 - 17:50
Coffee Break
Short Talks II
Yumiko Saga, Minoru Tanaka
17:50 - 18:05
“In Vitro Propagation of Presumptive Germ Cells with Primordial Germ Cell Characteristics Derived from Mouse Induced Pluripotent Stem Cells”
Masanori Imamura (Keio University, Japan)
18:05 - 18:20
“Acquisition of Pluripotency from Primordial Germ Cells”
Go Nagamatsu (Keio University, Japan)
18:20 - 18:35
“Nutrition-dependent Control of Ovarian Development by the Fat Body in Drosophila” Hiroko Sano (Kurume University, Japan)
18:35 - 18:50
“A Transient Niche for the Germline Stem Cell Precursors in Drosophila Ovary” Miho Asaoka (National Institute of Genetics, Japan)
18:50 - 19:05
“t-SNARE Syntaxin2 is Required for Transportation of Glycolipids and Stable Formation of Intercellular Bridges during Spermatogenesis”
Yasuhiro Fujiwara (Okayama University, Japan)
19:05 - 19:20
“Analysis of Epigenetic Changes Associating with Spermatogonial Stem Cell Differentiation”
Kazuyuki Ohbo (Yokohama City University, Japan)
July 20th (Fri) at OCC
The 58th NIBB Conference
Special Lectures
Robert E Braun, Shosei Yoshida
09:00 - 10:00
“The Germline: Evolution’s Trustee”
Allan C Spradling (Carnegie Institution for Science, USA)
10:00 - 10:10
Coffee Break
10:10 - 11:10
“Spermatogonial Stem Cells: Computer Simulation of Their Behaviour in the Stem Cell Niche” Dirk G de Rooij (University of Amsterdam, Netherlands)
Short Talks III
Yuzo Niki, Kyle E Orwig
11:10 - 11:25
“Propagation of Nile-tilapia Spermatogonial Stem Cells In Vitro”
Samyra Lacerda (Universidade Federal de Minas Gerais, Brazil)
11:25 - 11:40
“Establishment of Long-term Culture Conditions for Zebrafish Spermatogonial Stem Cells”
Noriyoshi Sakai (National Institute of Genetics, Japan)
“Stem Cell Renewal in the Drosophila Testis Niche”
Erika Matunis (Johns Hopkins University, USA)
15:30 - 16:10
“Cellular and Molecular Analyses of a Stable Drosophila Germline Stem Cell Niche Reconstructed In Vitro”
Yuzo Niki (Ibaraki University, Japan)
16:10 - 16:30
Coffee Break
16:30 - 17:10
“How are the Self-renewal and Differentiation of Mouse Spermatogenic Stem Cells Balanced?”
Shosei Yoshida (National Institute for Basic Biology, Japan)
17:10 - 17:50
“The Population Asymmetric Self-renewal of Germ Line Stem Cells” Benjamin D Simons (University of Cambridge, UK)
18:30 - 20:30
Mixer
July 21st (Sat) at OCC
The 58th NIBB Conference
Session V
Regulatory Mechanism of Germline Stem Cells
Robert E Braun, Takashi Shinohara
09:00 - 09:40
“Functional Compartmentalization of Murine Germ Cells and Translocation of Syncytial Chains across Sertoli Cell Tight Junctions”
Robert E Braun (The Jackson Laboratory, USA)
09:40 - 10:20
“In Vitro Transformation of Male Germline Stem Cells”
Takashi Shinohara (Kyoto University, Japan)
10:20 - 11:00
“Translating Spermatogonial Stem Cell Transplantation Toward the Clinic”
Kyle E Orwig (University of Pittsburgh, USA)
11:00 - 12:00
Lunch Break
Session VI
Manipulation of Germ Cells
Takehiko Ogawa, Goro Yoshizaki
12:00 - 12:40
“Avian Primordial Germ Cell: Its Culture and Manipulation for Transgenesis”
Jae Yong Han (Seoul National University, Korea)
12:40 - 13:20
“In Vitro Spermatogenesis Using an Organ Culture Method”
Takehiko Ogawa (Yokohama City University, Japan)
13:20 - 14:00
“Germ Cell Transplantation in Fish: Can Mackerel Produce Tuna?”
Goro Yoshizaki (Tokyo University of Marine Science and Technology, Japan)
Closing Remarks
14:00 - 14:10
Shosei Yoshida & Satoru Kobayashi (National Institute for Basic Biology, Japan)
Contact : conf58@nibb.ac.jp
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