National Insitute for Basic Biology
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Figure 1. A model for the regulation of meiosis by Mei2-RNA complexes in the fission yeast The function of Mei2 is required both prior to premeiotic DNA synthesis and prior to meiosis I. Mei2 complexes with meiRNA to promote meiosis l. This RNA is essential for the promotion, but it is not required for premeiotic DNA synthesis. Mei2 is likely to couple with another RNA partner to fulfill its function prior to premeiotic DNA synthesis, because the RNA-binding ability of Mei2 is indispensable to perform this function. (Adopted from ref. Watanabe and Yamamoto, 1994) |