{"id":4705,"date":"2019-12-09T15:38:31","date_gmt":"2019-12-09T06:38:31","guid":{"rendered":"https:\/\/www.nibb.ac.jp\/abis?p=4705"},"modified":"2022-04-29T14:02:56","modified_gmt":"2022-04-29T05:02:56","slug":"ac20191121","status":"publish","type":"post","link":"https:\/\/www.nibb.ac.jp\/abis\/ac20191121\/","title":{"rendered":"\u3010\u5149\u9855\uff1a\u677e\u7530\uff08\u4eac\u5927\uff09\u3011\u4f0a\u85e4\u79c0\u660e \u52a9\u6559\uff08\u611b\u77e5\u533b\u79d1\u5927\uff09\u306e\u8ad6\u6587\u304c Oncogene\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f"},"content":{"rendered":"\r\n<p>\r\n<b>\u3010\u5149\u5b66\u9855\u5fae\u93e1\u652f\u63f4\u62c5\u5f53\uff1a\u677e\u7530\u9053\u884c\uff08\u4eac\u90fd\u5927\u5b66\uff09\u3011[2019.11.21]<br>\r\n\u4f0a\u85e4\u79c0\u660e \u52a9\u6559\uff08\u611b\u77e5\u533b\u79d1\u5927\u5b66\uff09\u306e\u8ad6\u6587\u304c Oncogene \u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\r\n<\/b><br><br>\r\n\r\n\u304c\u3093\u7d30\u80de\u304c\u6b69\u304f\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u4e00\u7aef\u3092\u89e3\u660e \uff5e\u764c\u306e\u8ee2\u79fb\u3001\u6d78\u6f64\u5236\u5fa1\u306e\u70ba\u306e\u65b0\u305f\u306a\u6cbb\u7642\u6a19\u7684\u3068\u3057\u3066\u671f\u5f85\uff5e<br><br>\r\n<a href=\"https:\/\/www.nature.com\/articles\/s41388-019-1115-9\" rel=\"noopener\" target=\"_blank\">Ito H., Tsunoda T., Riku M., Inaguma S., Inoko A., Murakami H., Ikeda H., Matsuda M., Kasai K. Indispensable role of STIL in the regulation of cancer cell motility through the lamellipodial accumulation of ARHGEF7\u2013PAK1 complex. Oncogene, (2019) DOI:10.1038\/s41388-019-1115-9<\/a><br><br>\r\n\r\n\uff1c\u6982\u8981\uff1e\u672c\u7814\u7a76\u3067\u306f\u3001SCL\/TAL1 Interrupting Locus (STIL)\u304cARHGEF7\u3001PAK1\u3068\u8907\u5408\u4f53\u3092\u5f62\u6210\u3057\u3001\u3053\u308c\u3089RAC1\u6d3b\u6027\u56e0\u5b50\u306e\u764c\u7d30\u80de\u5148\u9032\u90e8\u3078\u306e\u96c6\u7a4d\u3068\u7d30\u80de\u9aa8\u683c\u518d\u69cb\u6210\u3001\u7d30\u80de\u904b\u52d5\u80fd\u306b\u5fc5\u9808\u3067\u3042\u308b\u3053\u3068\u3092\u5831\u544a\u3057\u307e\u3057\u305f\u3002ABiS\u30fb\u5149\u5b66\u9855\u5fae\u93e1\u652f\u63f4(\u652f\u63f4\u62c5\u5f53\uff1a\u677e\u7530\u9053\u884c\uff09\u3067\u306f\u3001Raichu-Rac1\u3092\u7528\u3044\u305f\u86cd\u5149\u5171\u9cf4\u30a8\u30cd\u30eb\u30ae\u30fc\u79fb\u52d5(FRET)\u89e3\u6790\u5b9f\u9a13\u3067\u306e\u7d30\u80de\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u652f\u63f4\u3092\u884c\u3044\u307e\u3057\u305f\u3002\r\n\r\n<\/p>\r\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u5149\u5b66\u9855\u5fae\u93e1\u652f\u63f4\u62c5\u5f53\uff1a\u677e\u7530\u9053\u884c\uff08\u4eac\u90fd\u5927\u5b66\uff09\u3011[2019.11.21] \u4f0a\u85e4\u79c0\u660e \u52a9\u6559\uff08\u611b\u77e5\u533b\u79d1\u5927\u5b66\uff09\u306e\u8ad6\u6587\u304c Oncogene \u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f \u304c\u3093\u7d30\u80de\u304c\u6b69\u304f\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u4e00\u7aef\u3092\u89e3\u660e \uff5e\u764c\u306e\u8ee2\u79fb\u3001\u6d78\u6f64\u5236\u5fa1\u306e\u70ba\u306e\u65b0\u305f\u306a\u6cbb\u7642 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5],"tags":[],"class_list":["post-4705","post","type-post","status-publish","format-standard","hentry","category-achievement"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.nibb.ac.jp\/abis\/wp-json\/wp\/v2\/posts\/4705","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nibb.ac.jp\/abis\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nibb.ac.jp\/abis\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nibb.ac.jp\/abis\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nibb.ac.jp\/abis\/wp-json\/wp\/v2\/comments?post=4705"}],"version-history":[{"count":2,"href":"https:\/\/www.nibb.ac.jp\/abis\/wp-json\/wp\/v2\/posts\/4705\/revisions"}],"predecessor-version":[{"id":7418,"href":"https:\/\/www.nibb.ac.jp\/abis\/wp-json\/wp\/v2\/posts\/4705\/revisions\/7418"}],"wp:attachment":[{"href":"https:\/\/www.nibb.ac.jp\/abis\/wp-json\/wp\/v2\/media?parent=4705"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nibb.ac.jp\/abis\/wp-json\/wp\/v2\/categories?post=4705"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nibb.ac.jp\/abis\/wp-json\/wp\/v2\/tags?post=4705"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}