文部科学省科学研究費特定領域研究「性分化機構の解明」 *

研究成果

篠田 晃 SHINODA, Koh
山口大学医学部高次神経科学講座神経解剖学
研究項目A02 「脳の性分化と行動の解析」
研究課題 性腺・副腎系ホルモンによる脳内ステロイド受容体発現とモノアミン作動系の制御
     (平成17年度〜平成18年度)
     ステロイドによる内側視索前野・扁桃体弓領域内アロマテースとステロイド受容体制御
     (平成19年度〜平成20年度)

2006年発表論文

Huntingtin-Associated Protein 1 (HAP1) Interacts with Androgen Receptor (AR) and Suppresses SBMA-Mutant-AR-Induced Apoptosis. Takeshita Y, Fujinaga R, Zhao C, Yanai A, Shinoda K. Hum Mol Genet. 2006 (in press)

G protein-coupled receptor 30 is an estrogen receptor in the plasma membrane. Funakoshi T, Yanai A, Shinoda K, Kawano MM, Mizukami Y. Biochem Biophys Res Commun. 2006, 346:904-910

Fibroblast growth factor 2 facilitates the differentiation of transplanted bone marrow cells into hepatocytes. Ishikawa T, Terai S, Urata Y, Marumoto Y, Aoyama K, Sakaida I, Murata T, Nishina H, Shinoda K, Uchimura S, Hamamoto Y, Okita K. Cell Tissue Res. 2006, Feb;323(2):221-31.

2005年発表論文

Ueda1, K., J. Kawano, K. Takeda, T. Yujiri, K. Tanabe, T. Anno, M. Akiyama, J. Nozaki, T. Yoshinaga, A. Koizumi, K. Shinoda, Y. Oka, and Y. Tanizawa (2005) Endoplasmic Reticulum Stress Induces Wfs1 Gene Expression in Pancreatic β-cells via Transcriptional Activation. Eur J Endocrinol. 2005, Jul;153(1):167-76.

2004年発表論文

Fujinaga, R., J. Kawano, Y. Matsuzaki, K. Kamei, A. Yanai, Z. Sheng, M. Tanaka, K. Nakahama, M. Nagano and K. Shinoda (2004) Neuroanatomical distribution of Huntingtin-associated protein 1 (Hap1)-mRNA in the Male mouse brain. J. Comp. Neurol. 478:88-109.

Sheng, Z., J. Kawano, A. Yanai, R. Fujinaga, M. Tanaka, Y. Watanabe and K. Shinoda (2004) Expressions of estrogen receptors (α,β) and androgen receptor in serotonin neurons of the rat and mouse dorsal raphe nuclei; sex and species differences. Neurosci. Res. 49:185-196.

Liu, Y., Y. Ishida, K. Shinoda, S. Furukawa, S. Nakamura (2004) Opposite morphological responses of partially denervated cortical serotonergic and noradrenergic axons to repeated stress in adult rats. Brain Res. Bull. 64:67-74.

Yamamoto, N., S. Terai, S. Ohata, T. Watanabe, K. Omori, K. Shinoda, K. Miyamoto, T. Katada, I. Sakaida, H. Nishina, and K. Okita (2004) A subpopulation of bone marrow cells depleted by a novel antibody, anti-Liv8, is useful for cell therapy to repair damaged liver. Biochem. Biophys. Res. Comm. 313 1110-1118.

Omori, K., S. Terai , T. Ishikawa , T. Ishikawa, K. Aoyama, I. Sakaida, H. Nishina, K. Shinoda, S. Uchimura, Y. Hamamoto, and K. Okita (2004) Molecular signature associated with plasticity of bone marrow cell under persistent liver damage by self-organizing-map-based gene expression. FEBS Letters, 578:10-20