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FUNCTIONAL GENOMICS FACILITY

 

Faculty

SHIGENOBU, Shuji

Specially appointed Associate Professor
SHIGENOBU, Shuji

Research Summary

Symbiosis has contributed to the ecological and evolutionary success of many taxa by provisioning novel traits, thereby facilitating exploitation of otherwise inaccessible niches. We are studying the symbiosis of the pea aphid with the bacterial symbiont Buchnera to understand the network of biological interactions at the molecular and genetic level. To this end, we take advantage of state-of-the-art genomics such as next-generation sequencing technologies.

PhD Program

This laboratory is currently recruiting graduate students.

Reports

Selected Publications

Shigenobu, S., & Wilson, A. C. C. (2011). Genomic revelations of a mutualism: the pea aphid and its obligate bacterial symbiont. Cellular and molecular life sciences : CMLS, 68(8), 1297-1309.

The International Aphid Genomics Consortium. (2010). Genome Sequence of the Pea Aphid Acyrthosiphon pisum. PLoS Biol., 8(2):e1000313.

Shigenobu, S., Kitadate, Y., Noda, C. and Kobayashi, S. (2006). Molecular characterization of the embryonic gonads by gene expression profiling in Drosophila melanogaster. Proc. Natl. Acad. Sci. U. S. A., 103, 13728-13733

Nakabachi, A., Shigenobu, S., Sakazume, N., Shiraki, T., Hayashizaki, Y., Carninci, P., Ishikawa, H., Kudo, T. and Fukatsu, T. (2005). Transcriptome analysis of the aphid bacteriocyte, the symbiotic host cell that harbors an endocellular mutualistic bacterium, Buchnera. Proc. Natl. Acad. Sci. U. S. A., 102, 5477-5482.

Shigenobu, S., Watanabe, H., Hattori, M., Sakaki, Y. and Ishikawa, H. (2000). Genomesequence of the endocellular bacterial symbiont of aphids Buchnera sp APS. Nature, 407, 81-86.

Contact

Associate Professor(Specially appointed) SHIGENOBU, Shuji TEL: +81 564 55 7672  E-mail: shige@nibb.ac.jp