日本語

National Institutes of Natural Sciences

National Institute for Basic Biology

NIBB Departments

Laboratory for Spatiotemporal Regulations

Faculty

NONAKA, Shigenori
Associate Professor
NONAKA, Shigenori
YOKE, Hiroshi
Specially Appointed Assistant Professor
YOKE, Hiroshi

Research Summary

In spite of superficially bilateral symmetry, our bodies are highly asymmetric along the left-right (L-R) axis, for example in the placement of internal organs. Our main aim is to clarify the mechanism by which mammalian embryos generate and establish the L-R asymmetry.

PhD Program

This laboratory is currently recruiting graduate students.

Website

Reports

Selected Publications

Maruyama, A., Oshima, Y., Kajiura-Kobayashi, H., Nonaka, S., Imamura, T., and Naruse, K. (2014). Wide field intravital imaging by two-photon-excitation digital-scanned light-sheet microscopy (2p-DSLM) with a high-pulse energy laser. Biomed Opt Express 5, 3311-3325.
 
Ichikawa, T., Nakazato, K., Keller, P. J., Kajiura-Kobayashi, H., Stelzer, E. H., Mochizuki, A., and Nonaka, S. (2013). Live imagingof whole mouse embryos during gastrulation: migration analysesof epiblast and mesodermal cells. PLoS One. 8, e64506.
 
Takao, D., Nemoto, T., Abe, T., Kiyonari, H., Kajiura-Kobayashi,H., Shiratori, H., and Nonaka, S. (2013). Asymmetric distribution ofdynamic calcium signals in the node of mouse embryo during leftrightaxis formation. Dev. Biol. 376, 23-30.
  
Nonaka, S., Shiratori, H., Saijoh, Y., and Hamada, H. (2002). Determination of left-right patterning of the mouse embryo by artificial nodal flow. Nature 418, 96-99.

Contact

Associate Professor NONAKA, Shigenori TEL: +81 564 55 7590 E-mail: snonaka@nibb.ac.jp